Free radicals, metals and antioxidants in oxidative stress-induced cancer.

By M. Valko, C. Rhodes, J. Moncol’, Mário Izakovič, M. Mazúr. Chemico-Biological Interactions, 2006

6,766 citations recorded by the source corpus.

Subfields: Molecular Biology, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/4e63d22101230e390d005ce5ab691b98322eeba6

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Citations in the corpus

Oxidative stress in neurodegenerative diseases (2012, background): “Exogenous ROS result from air and water pollution, cigarette smoke, alcohol, heavy or transition metals (Cd, Hg, Pb, Fe, As), certain drugs (cyclosporine, tacrolimus, gentamycin, bleomycin), industrial solvents, cooking (smoked meat, used oil, fat) and radiation [9-12] .”
Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review (2014, background): “PUFA are attacked by a radical at an internal position or near the end of the conjugated system, generating a peroxyl radical (LOO ) [81].”
Heavy Metals Toxicity and the Environment (2012, background): “Antioxidant enzymes serve as a line of cellular defense against mercury compounds [213].”
Agro-industrial potential of the mango peel based on its nutritional and functional properties (2016, background): “degenerative ailments such as cancer, arthritis, aging, autoimmune disorders, and cardiovascular and neurodegenerative diseases.((32)) The antioxidant activity is extremely important for protection against diseases related to oxidative stress.”
Oxidative Stress: Harms and Benefits for Human Health (2017, background): “Hydrolyzed DNA bases are common byproducts of DNA oxidation and are considered one of the most relevant events in chemical carcinogenesis [14, 22].”
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis (2006, background): “The resultant damage to DNA or proteins, directly affects the various stress-signalling and/or checkpoint-signalling pathway”
Chronic inflammation and oxidative stress in human carcinogenesis (2007, background): “In the carcinogenesis also, the oxidative damage of mitochondria is strongly involved.(42) In fact,”
Regulation of reactive oxygen species generation in cell signaling (2011, background): “While moderate levels of ROS are useful for cellular proliferation and host defense, excessive amounts of ROS can be harmful to cellular metabolism and cause unwanted events, such as damage to DNA, RNA, and proteins, and induction of apoptosis or necrosis (Valko et al., 2006).”
A Comprehensive Review on Lipid Oxidation in Meat and Meat Products (2019, background): “This reaction is effective when Fe3+ can be reduced to Fe2+ by reducing compounds [46] and it can involve other ions such as Cu2+, Ti4+, and Co3+ [95,96].”