Immune cell migration in inflammation: present and future therapeutic targets

By A. Luster, R. Alon, Ulrich H. von Andrian. Nature Immunology, 2005

1,351 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy, Oncology

View Paper: https://www.semanticscholar.org/paper/325fe5881ea7ce80fed07b71dbe54da5201a96c6

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In Immunology

1. C. Serhan
2. Frank O. Nestle
3. R. Flavell
4. P. Di Meglio
5. Chia Nan
6. R. Medzhitov
7. R. Ransohoff
8. Shizuo Akira

In Immunology and Allergy

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In Oncology

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2. R. Flavell

Citations in the corpus

• Skin immune sentinels in health and disease (2009, background): “Initial views of skin immunosurveillance emphasized the importance of immune cells that circulate between skin-draining lymph nodes and peripheral tissue and that can react quickly to antigen challenge”
• Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool (2011, background): “Blocking the migration of immune cells across the BBB has long been regarded as a likely therapeutic approach for treating CNS-directed autoimmune disease”
• Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. (2008, background): “Since a previous report indicated that the blood-brain barrier (BBB) may be dysfunctional in PD patients (11), we examined whether MPTP-associated BBB disruption could account for a passive entry of lymphocytes into the brain.”
• Regulation of Inflammation by Short Chain Fatty Acids (2011, background): “extravascular space, leukocytes sense distinct sets of chemoattractants and move in the direction of the inflammatory foci [19].”
• A cytokine-mediated link between innate immunity, inflammation, and cancer. (2007, neutral): “The inflammatory milieu is occupied by cells such as resident and recruited macrophages, DCs, T cells, and NK cells (11).”
• Inflammation and pregnancy: the role of the immune system at the implantation site (2011, background): “Either of these possibilities or their combination can represent the response of the endometrial epithelium to DCs recruited to the site of implantation.”
• Immunobiology of mesenchymal stem cells (2013, background): “cells, not only macrophages and neutrophils but also adaptive immune cells, including CD4þ T cells, CD8þ T cells and B cells, which are recruited by factors from apoptotic cells, necrotic cells, damaged microvasculature and stroma.(19,20) Meanwhile, inflammatory mediators, such as TNF-a, IL-1b, free”
• Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators (2008, background): “These chemoattractants consist of endogenous lipid mediators, such as leukotrienes , and protein mediators, including chemokines and cytokine”