Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

By C. Serhan, Chia Nan, T. V. Van Dyke. Nature reviews. Immunology, 2008

2,939 citations recorded by the source corpus.

Subfields: Biochemistry, Nutrition and Dietetics, Surgery

View Paper: https://www.semanticscholar.org/paper/be4f97082bc350f78fc24d1d3dcb24e6a7b65517

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Citations in the corpus

The Cellular Biology of Macrophages in Atherosclerosis (2011, neutral): “Strategies being explored include proinflammation resolution mediators such as lipoxins, resolvins, and interleukin-10 receptor activators (Serhan et al., 2008); MerTK inhibitors of cleavage (Sather et al.”
Resolvins RvE1 and RvD1Attenuate Inflammatory Pain via Central and Peripheral Actions (2010, background): “Recently, resolvins, a unique family of lipid mediators, including RvE1 and RvD1 derived from omega-3 polyunsaturated fatty acid, have shown marked potency in treating disease conditions associated with inflammatio”
Omega-3 fatty acids EPA and DHA: health benefits throughout life. (2012, background): “In addition, because potent lipid mediator metabolites of EPA and DHA are of great interest currently, their influence on these important outcomes should be assessed because current evidence suggests that their antiinflammatory and tissue-protective effects are nearly 1000 times greater than those o”
Oxidative Stress in Cardiovascular Diseases: Still a Therapeutic Target? (2019, background): “For example, n-3 PUFA-derived lipid mediators, namely resolvins, protectins and maresins, have been ascribed anti-inflammatory properties [132].”
Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA (2015, background): “…18:3n-3) and stearidonic acid (SDA, 18:4n-3) have shown potential health benefits (Barceló-Coblijn and Murphy, 2009; Whelan, 2009), these have yet to be sufficiently explored in the context of central nervous system (CNS) disorders, and therefore this review will be restricted to EPA, DPA and DHA.”
Pro-Resolving lipid mediators and Mechanisms in the resolution of acute inflammation (2014, background): “…and the more recently discovered omega-3 derived ‘specialized pro-resolution mediators’ represent the key signaling molecules in this process (Figures 1 and 2), which regulate the inflammatory profile and promote the return of affected tissues to homeostasis (Serhan, 2010; Serhan et al., 2008).”
Trends in the Use of Complementary Health Approaches Among Adults: United States, 2002–2012 (2015, background): “Research has suggested that fish oil can reduce blood pressure (31) and inflammation (32), increase brain blood flow (33), and provide structural strength for neurons (34,35).”
The Multifaceted Role of Annexin A1 in Viral Infections (2023, background): “The successful resolution of inflammation in the affected site depends on a wide variety of factors, including the clearance of pathogens, the switch from pro-inflammatory molecules to anti-inflammatory mediators, the inhibition of neutrophil recruitment, and the non-phlogistic recruitment of macrop”
NF-κB, an Active Player in Human Cancers (2014, positive): “Inflammation progression can be categorized at the acute, adaptive, and resolution stages (11).”
Impact of Obesity and Metabolic Syndrome on Immunity. (2016, background): “Proper function and defense conferred by these systems depends on sophisticated developmental and maturation processes in lymphoid tissues, including the bone marrow, thymus, spleen, and lymph nodes (22, 23), and the intricate coordination of innate and adaptive immune responses—from appropriately i”