Exploring and engineering the cell surface interface.

By Molly M. Stevens, Julian H. George. Science, 2011

652 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Biophysics

View Paper: https://www.semanticscholar.org/paper/303bf651eea4eadf677d93fabc4044f6a6dfc150

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In Biomedical Engineering

In Biophysics

Citations in the corpus

An algorithm-based topographical biomaterials library to instruct cell fate (2011, background): “The underlying mechanisms defining the interplay of cells with substrates are only partially understood (12 – 15).”
The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. (2007, methodology): “Following the observed significant affect of nanotopography on the mesenchymal population, osteospecific macroarrays were used to compare MSC differentiation for cells cultured on (1) DSQ50, (2) planar material with dexamethasone (DEX), a corticosteroid that can induce bone formation and (3) untreat”
Review of bioactive glass: from Hench to hybrids. (2013, background): “provide beneficial cellular response in certain applications [266].”
Intrinsic extracellular matrix properties regulate stem cell differentiation. (2010, background): “By only attaching its basal surface to the material (Stevens and George, 2005), mechanotransduction mechanisms of the cell may be similar to”
Physical approaches to biomaterial design (2009, background): “, have been shown to mitigate a series of cellular function”
Complexity in biomaterials for tissue engineering. (2009, background): “, and the importance of other physical features such as topography and three-dimensionality of the matrix has been reviewed or demonstrated elsewher”
Recent advances in 3D printing of biomaterials (2015, methodology): “When making scaffolds, design of the architecture on the macro, micro, and nano level is important for structural, nutrient transport, and cell-matrix interaction conditions [1-3].”
Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs (2009, background): “L cells and tissues can display high sensitivity to local micro- and nanoscale molecular and topographic patterns, including those provided in vivo by complex and well-defined structures of extracellular matrix (ECM) (1).”
Three-Dimensional Cell Culture Matrices: State of the Art (2008, background): “Nano-scale surface topography has been demonstrated to regulate cell adhesion, organization, morphology, and differentiation.(38) Still, compared with surface chemistry, limited 3D nano-scale fabrication techniques leave the effects of surface topology insufficiently investigated.”
Engineering microscale topographies to control the cell–substrate interface (2012, background): “The ECM is composed of proteins and polysaccharides with structural widths and lengths in the nanoand micrometer range, respectively [7].”
Bioactive Glass and Glass-Ceramic Scaffolds for Bone Tissue Engineering (2010, background): “, the design and incorporation of nano-topographic features on the scaffold surface architecture, in order to mimic the nanostructure of natural bone, is also becoming a significant area of research in bone tissue engineering [10,82-84].”