Three-Dimensional Cell Culture Matrices: State of the Art

By Jungwoo Lee, Meghan J. Cuddihy, Nicholas A. Kotov. Tissue engineering. Part B, Reviews, 2008

1,049 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/0aa61f611aad545a9905685c31680673bb0bc3e3

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In Biomedical Engineering

Citations in the corpus

A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering. (2012, background): “Other advantages comprise: high degree of interconnectivity, possibility to use heterogeneous materials, high speed due to a high degree of automization and the limited number of process steps, and a superior cost-efficiency [3,65].”
Current trends in the design of scaffolds for computer-aided tissue engineering. (2014, background): “To date, additive manufacturing of clinically sized tissues with high anatomical precision has been primarily demonstrated for hard tissues such as bone and cartilage [58,133,134], while soft tissue applications, albeit strongly emphasized for their pivotal role”
Additive manufacturing of tissues and organs (2012, background): “Although a significant body of knowledge on cell behavior has been accumulated using patterned surfaces, two-dimensional (2D) techniques have been shown to be insufficient for some new challenges of cell biology and biochemistry, as well as in pharmaceutical assays [23].”
Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties (2018, background): “Therefore, many important characteristics of cells with an adhesive type of growth in a monolayer culture substantially differ from those of the same cells in the living tissue; hence, conclusions from many experiments on the NP toxic effects on cells growing in a monolayer are somewhat incorrect [1”
Cross-linking in Hydrogels - A Review (2014, background): “Classification of hydrogels: Hydrogels can be classified into physical and chemical hydrogels based on their cross-linking mechanism [19, 28].”
Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells. (2010, background): “Interestingly, these cell responses have been shown to occur similarly in vivo and in 3D rather than in 2D [40,57,58].”
Intrinsic extracellular matrix properties regulate stem cell differentiation. (2010, background): “While the planar versus 3D discussion has been extensively reviewed (Burdick and Vunjak-Novakovic, 2008; Chan and Mooney, 2008; Lee et al., 2008), what may be missing from the dialogue has been a focus on improving the mimicry and functionality of a biomaterial scaffold to produce more…”
2D and 3D cell cultures – a comparison of different types of cancer cell cultures (2016, methodology): “Cells interactions Deprived of cell-cell and cellextracellular environment interactions, no in vivo-like microenvironment and no “niches” Proper interactions of cell-cell and cell-extracellular environment, environmental “niches” are created [13, 28, 29, 36, 37]”