The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder.

By Matthew J. Dalby, Nikolaj Gadegaard, Rahul S. Tare, A. Andar, M. Riehle, P. Herzyk, C. Wilkinson, R. Oreffo. Nature Materials, 2007

2,343 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Cell Biology

View Paper: https://www.semanticscholar.org/paper/ad3d7a414b3f2b3f85645d616c6aa5d3ecdd13b9

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Citations in the corpus

Nanotopography-guided tissue engineering and regenerative medicine (2012, background): “reported that the osteogenic differentiation and self-renewal of MSCs are mediated by nano patterned substrates [144,145,158] (Fig.”
Fate decision of mesenchymal stem cells: adipocytes or osteoblasts? (2016, background): “Nanoscale disorders have been shown to stimulate MSC differentiation into osteoblasts in the absence of osteogenic inducers.(112) In addition, by culturing geometrically patternedMSCs in medium containing both adipogenic and osteogenic chemical inducers, it has been shown that geometric cues of nati”
Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs (2009, background): “Studies of engineered cell–biomaterial interactions at the subcellular, nanoscale levels are providing evidence for potential importance of submicrometer cues for cell signaling (2), adhesion (3–5), growth (6), and differentiation (7, 8).”
An algorithm-based topographical biomaterials library to instruct cell fate (2011, background): “Micro-meter-range patterning is used to align cells on biomaterial surfaces (8 – 10), whereas Dalby et al. reported that randomly placed nanotopographies were able to induce osteogenic differentiation of MSCs (11).”
Osteoinductive ceramics as a synthetic alternative to autologous bone grafting (2010, background): “For instance, in the area of biomaterials for the restoration of bone defects, it has been reported that surface topography influences osteogenesis and proliferation of bone marrow-derived multipotent mesenchymal stromal cells (MSCs) in vitro (6, 7).”
Stem cell fate dictated solely by altered nanotube dimension (2009, background): “(7) reported that MSC cultured on highly ordered poly(methylmethacrylate) (PMMA) nanopatterns showed negligible osteogenic differentiation, but randomized PMMA nanotopography demonstrated MSC osteoblastic morphologies after 21 days of incubation with cell growth media.”
A review on the wettability of dental implant surfaces II: Biological and clinical aspects. (2014, background): “The moderate immune response [74] and lower activation of thrombocytes [80], found on hydrophilic surfaces compared to hydrophobic ones can facilitate the invasion and mobilization of the blood clot by mesenchymal stem cells (MSCs) [81], considered as one of the initial non-hematopoietic cell types ”
The interaction of cells and bacteria with surfaces structured at the nanometre scale. (2010, methodology): “4) inwhichnanoscale surface topographyalone was responsible for the differentiation of stem cells into bone cells [103].”
The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation. (2009, neutral): “and human mesenchymal stem cells [13].”
The regulation of tendon stem cell differentiation by the alignment of nanofibers. (2010, background): “Both the matrix-elasticity and the substrate patterning influence the specification of stem cell lineage [19,20].”
Harnessing nanotopography and integrin-matrix interactions to influence stem cell fate. (2014, background): “unique tissues and organs of the body [34].”