Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes

By B. Tu, A. Kudlicki, Maga Rowicka, S. McKnight. Science, 2005

922 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/2acf201135da256738bfbaaaa4e3d8bd60c63495

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In Molecular Biology

Citations in the corpus

Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes (2011, methodology): “Through comprehensive transcript and metabolite profiling studies, we have previously uncovered the temporal sequence of transcriptional and metabolic outputs as cells exit the quiescent-like (RC) phase and enter the growth (OX) and division (RB) phases (Rowicka et al., 2007; Tu et al., 2005; Tu et ”
Influence of Metabolism on Epigenetics and Disease (2013, positive): “For example, prototrophic (wild-type) strains of yeast grown in the nutrient-limiting environment of a chemostat spontaneously enter a synchronous and highly robust metabolic cycle (Klevecz et al., 2004; Tu et al., 2005; Tu and McKnight, 2006, 2009; Tu et al., 2007).”
Acetyl-CoA and the Regulation of Metabolism: Mechanisms and Consequences (2015, background): “During the yeast metabolic cycle (YMC), many ATG genes (including ATG1 and ATG8) are repressed during growth phases when acetyl-CoA levels rise, and are activated only during the stress/survival phases when acetyl-CoA levels fall [21,22].”
Permutation test for periodicity in short time series data (2006, neutral): “We would like to thank two of the co-authors of the Tu et al. [2] publication, Drs. Rowicka and Kudlicki (UT-Southwestern), for bringing this to our attention.”
Timing of food intake predicts weight loss effectiveness (2013, background): “Thus, a specific temporal order in the daily patterns of these genes appears to be crucial for adipose tissue to exclusively either accumulate fat or to mobilize fat at the proper time, a phenomenon known as temporal compartmentalization (18).”
Metabolic regulation of epigenetics (2012, background): “Remarkably, when genome-wide gene expression in yeast under such culture system was analyzed, nearly 60% of the genes were expressed in a similarly cyclic fashion (Klevecz et al., 2004; Tu et al., 2005).”
Nutritional Control of Growth and Development in Yeast (2012, background): “These cycles are correlated with specific cyclical changes in expression of a large number of genes (Klevecz et al. 2004; Tu et al. 2005).”
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities (2006, methodology): “We validate the model both on synthetic data and real data from two yeast time series: the benchmark cell cycle data set of Spellman et al. (1998) and the recent metabolic cycle data set of Tu et al. (2005).”
Quantum metrology and its application in biology (2014, background): “The period of cyclic processes varies substantially; Saccharomyces cerevisiae yeast exhibits both 40 minute and daily cycles in activity [133].”
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. (2011, positive): “Also, budding yeast S. cerevisiae display robust, periodic cycles of glycolytic and respiratory metabolism in nutrient-limited conditions (Tu et al 2005).”