The emerging shape of the ESCRT machinery

By Roger L. Williams, S. Urbé. Nature reviews. Molecular cell biology, 2007

772 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/278012eb781960327fd094f6aa88144a36d9a3e9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. G. Raposo
2. Harald A. Stenmark
3. Suresh Mathivanan
4. Richard J. Simpson
5. H. Ji
6. Ivan Dikic
7. C. Raiborg
8. W. Henne

In Molecular Biology

1. Suresh Mathivanan
2. Richard J. Simpson
3. H. Ji
4. G. Raposo
5. Ivan Dikic
6. M. Simons
7. Harald A. Stenmark
8. Soichi Wakatsuki

In Physiology

1. G. Raposo
2. Suresh Mathivanan
3. Richard J. Simpson
4. H. Ji
5. W. Henne
6. Ivan Dikic
7. Harald A. Stenmark
8. C. Raiborg

Citations in the corpus

• Ubiquitin-binding domains — from structures to functions (2009, background): “The structural details of isolated components and their complexes have been revealed for each of the ESCRT assemblies in recent year”
• Exosomes: extracellular organelles important in intercellular communication. (2010, background): “With the aid of three-dimensional structural studies, key links between the components of the ESCRT multiprotein complex, phospholipids and ubiquitin are beginning to shed new insights into MVB biogenesis and trafficking [10].”
• The ESCRT pathway. (2011, background): “For more in-depth discussion, the reader should refer to several reviews that focus on ESCRT structure, ESCRT roles in diseases, the ubiquitin cycle, and vesicle budding (Hurley et al., 2010; Raiborg and Stenmark, 2009; Saksena and Emr, 2009; Williams and Urbé, 2007).”
• HECT and RING finger families of E3 ubiquitin ligases at a glance (2012, background): “…role for RTK ubiquitylation by CBL in the initial receptor internalization step is unclear, but ongoing ubiquitylation of RTKs by this E3 ligase is necessary for correct downstream sorting and degradation of the signaling complex by the lysosome (Marmor and Yarden, 2004; Williams and Urbe, 2007).”
• Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles (2010, background): “In this process, four proteins, ESCRT-0, -I, -II, and -III, are successively recruited to vesicle budding sites (82).”
• Multivesicular Endosome Biogenesis in the Absence of ESCRTs (2009, background): “The four cytoplasmic protein complexes ESCRT-0, ESCRT-I, ESCRT-II and ESCRT-III consist of at least 13 class E vps proteins that have been conserved from yeast to humans (10).”
• The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins (2009, methodology): “Structural information is available for all ESCRTs, and the detailed structural biology of the ESCRTs has recently been described in excellent review”
• Exosomes--vesicular carriers for intercellular communication. (2009, background): “The role of the ESCRT (endosomal sorting complex required for transport) machinery in this process is well appreciated [18,19].”