Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

By Yuen Ho, A. Gruhler, Adrian Heilbut, Gary D. Bader, L. Moore, S. Adams, A. Millar, Paul Taylor, K. Bennett, K. Boutilier and 36 more. Nature, 2002

3,736 citations recorded by the source corpus.

Subfields: Food Science, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/1df327ba125dcdb9845b2d9feeca82bba6c197a0

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Citations in the corpus

Global protein function prediction in protein-protein interaction networks (2003, background): “Previous approaches to deduce the unknown function of a class of proteins have exploited sequence similarities or clustering of co-regulated genes [2,3], phylogenetic proﬁles [4], protein-protein interactions [5,6,7,8], and protein complexes [9,10].”
Prediction of Protein Function Using Protein–Protein Interaction Data (2002, background): “, 2000) and the mass spectrometric analysis of protein complexes (Gavin et al., 2002; Ho et al., 2002).”
Exploring genetic interactions and networks with yeast (2007, background): “Partial but significant collections of genes have been constructed encoding GAL1 -regulated proteins, which are either untagged or carry a carboxy (C)-terminal Flag epitop”
A versatile toolbox for PCR‐based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes (2004, background): “These strategies have been shown to be powerful tools in systematic gene deletion, protein localization and protein complex purification (Gavin et al., 2002; Ho et al., 2002), as well as for single gene-function analysis.”
A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling (2003, background): “EGFR has been found in the nucleus, and there is increasing, if controversial, evidence of direct nuclear functio”
Deciphering Protein–Protein Interactions. Part I. Experimental Techniques and Databases (2007, methodology): “Several large-scale studies of protein complexes have been performed using TAP–MS and Y2H methods [2,4,63,64].”
The ClusPro web server for protein-protein docking (2017, background): “Substantial progress has been made toward generating potential protein–protein interaction networks using high-throughput proteomics studies, primarily yeast two-hybrid assays 1,2 and mass spectrometry 3,4 .”
MATRIX-ASSISTED LASER DESORPTION MASS SPECTROMETRY (2002, background): “about the function and importance of previously identified and newly observed proteins.([64]) Researchers also located and characterized hypothetical proteins predicted from the yeast genome sequence.”
IntAct: an open source molecular interaction database (2004, background): “Data content and submission IntAct currently contains ~2200 interactions, mainly imported from large-scale experiments (3, 9 ), and a growing number of interactions extracted from the literature by the IntAct and Swiss-Prot curation teams.”
A Protein Complex Network of Drosophila melanogaster (2011, methodology): “…purification combinedwith tandemmass spectrometry (coAP-MS) has been used to generate protein complex maps at proteome scale for Saccharomyces cerevisiae (Gavin et al., 2006; Ho et al., 2002; Krogan et al., 2006), Escherichia coli (Hu et al., 2009), and Mycoplasma pneumoniae (Kühner et al., 2009).”
Multiple associated proteins regulate proteasome structure and function. (2002, background): “…the proteasome base and its subunit Rpn1, suggesting that protea- used to survey proteins that interact with proteasomes (Verma et al., 2000, 2001; Ho et al., 2002; Gavin et al.,some binding positions Ubp6 proximally to the substrate translocation channel. ubp6 mutants exhibit 2002; Davy et al.,…”
Recent progress and future directions in protein-protein docking. (2008, neutral): “1389-2037/08 $55.00+.00 © 2008 Bentham Science Publishers Ltd. Keywords: Protein-protein docking, protein-protein interactions, docking algorithms, data-driven docking, molecular dynamics, protein structure databases, protein interface prediction, CAPRI.”