Immune recognition. A new receptor for beta-glucans.

By G. D. Brown, S. Gordon. Nature, 2001

697 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/1c4ebbcf3d68df7b68d6e8b0fa4040cda4c1d79f

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Citations in the corpus

Role of yeast cell wall polysaccharides in pig nutrition and health protection (2007, background): “, 2002), and Dectin-1 (Brown and Gordon, 2001).”
Dectin-1: a signalling non-TLR pattern-recognition receptor (2006, background): “Both of these receptors act as PRRs, recognizing microbial component”
Dectin-1 is required for β-glucan recognition and control of fungal infection (2006, background): “Host-cell recognition of β-glucan is mediated mainly by dectin-1, a myeloid-expressed type II transmembrane C-type lectin–like receptor that contains an immunoreceptor tyrosine-based activation motif in its cytoplasmic tai”
Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms (2006, background): “, 2002) or dectin (Brown and Gordon, 2001) may be involved.”
DC-SIGN: escape mechanism for pathogens (2003, background): “Both DC-SIGN and dectin-1 contain ITAMs, whereas DCIR contains an immunoreceptor tyrosine-based inhibitory motif (ITIM”
Dectin-1 Mediates the Biological Effects of β-Glucans (2003, background): “To explore the possibility that Dectin-1 was involved in mediating the proinflammatory responses to -glucans, we examined the effect of GluP, a potent soluble -glucan inhibitor of Dectin-1 (8), on the ability of zymosan to induce TNF- production in primary M (Fig.”
Macrophage heterogeneity in tissues: phenotypic diversity and functions (2014, unknown): “The function of Dectin-1as a b-glucan receptor was discovered by a screen using zymosan particles (26).”
Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2 (2003, background): “Although dectin-1 expression in nonphagocytic cells such as NIH3T3 cells (14) or HEK 293 cells (unpublished data) is sufficient to confer the ability to internalize zymosan particles, phagocytosis of fluorescently labeled zymosan was only mildly enhanced in RAW cells overexpressing dectin-1 (Fig.”
Dectin-1 Is A Major β-Glucan Receptor On Macrophages (2002, methodology): “408 Dectin-1 Is a Major -Glucan Receptor on Macrophages rather we demonstrate that the recently described Dectin-1 (17, 18) plays a major role in this process.”
Pattern recognition receptors and control of adaptive immunity (2009, background): “Dectin-1 recognizes b-glucans that are unique, to microbial non-self (30).”