Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome

By Shin-ichi Horike, S. Cai, M. Miyano, Jan-Fang Cheng, T. Kohwi-Shigematsu. Nature Genetics, 2005

634 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/1bbe5a76564aba62a341415cee37100d119436dc

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Citations in the corpus

Beyond the sequence: cellular organization of genome function. (2007, positive): “, 2004), and the maternally expressed DLX5 locus (Horike et al., 2005).”
Inflammatory Networks during Cellular Senescence: Causes and Consequences (2010, background): “These loci are roughly the size of chromatin loops, which are an important unit of chromatin organization and transcriptional control [73].”
A decade of 3C technologies: insights into nuclear organization. (2012, background): “As such, it is a genome-wide version of the ChIP-loop procedure (Horike et al. 2005).”
Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. (2007, background): “Despite extensive effort, only a few genes, including BrainDerived Neurotrophic Factor (Chen et al., 2003; Martinowich et al., 2003), DLX5 and 6 (Horike et al., 2005), and inhibitor of differentiation (ID1, 2, 3 and 4) genes (Peddada et al., 2006) have been shown to be regulated by Mecp2.”
Maternal care as a model for experience-dependent chromatin plasticity? (2005, background): “MeCP2 also facilitates chromatin inactivation through chromatin looping [ 45 ] and recruitment of Brahma (Brm), a catalytic component of the SWI/SNF-related chromatin-remodelling complex [46,47].”
Hi-C: A comprehensive technique to capture the conformation of genomes (2012, positive): “In special variants of the 3C technology (ChIP-loop and ChIA-PET), immunoprecipitation is used to associate the interactions with a particular protein of interest [5, 6].”
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. (2006, background): “It has been shown previously that Dlx-2 activates the Wnt-1 enhancer (Iler et al. 1995) in the mouse C2C12 muscle cell line (Zhang et al. 1997).”
Computational and experimental identification of novel human imprinted genes. (2007, background): “Conversely, the homeobox gene DLX5 is imprinted in human (Okita et al. 2003) but not mouse (although a subtle maternal preference was reported in the mouse brain) (Kimura et al. 2004; Horike et al. 2005).”
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. (2005, background): “Recently, MeCP2 was shown to silence genes via a looped structure involving distinct sites (Horike et al., 2005).”
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions (2006, background): “Three different sequences representing interactions present only in undifferentiated cells (1), in both differentiated and undifferentiated cells (2) or only in differentiated cells (3) were picked and hybridized with 4C samples from undifferentiated and differentiated ES cells.”
Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state (2010, background): “, 2003) and at the Dlx5/6 locus (Horike et al., 2005).”
DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG. (2005, positive): “A similar study of mouse brain chromatin using an antiMeCP2 antibody identified the mouse Dlx5/Dlx6 genes as targets for MeCP2-mediated repression (Horike et al., 2005).”