Maternal care as a model for experience-dependent chromatin plasticity?

By Michael Joseph Meaney, M. Szyf. Trends in Neurosciences, 2005

634 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Pediatrics, Perinatology and Child Health, Social Psychology

View Paper: https://www.semanticscholar.org/paper/3af6ca915a6f51d3125fe8651ef219bc53351b4a

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Citations in the corpus

How Elephants are Opening Doors: Developmental Neuroethology, Attachment and Social Context (2007, background): “Not only does the caregiver’s behaviour guide the infant’s stress responses through neuroethological patterning, but does so through tissuespecific effects on gene expression (Meaney & Szyf 2005).”
Glucocorticoids, prenatal stress and the programming of disease. (2011, positive): “crucially, rodent models show that early environmental challenges (such as restraint stress in third week of pregnancy) increase anxiety and depressive-like behaviour and impair cognitive ability in adults, further substantiating the human correlative data (Meaney and Szyf, 2005).”
Research review: the neurobiology and genetics of maltreatment and adversity. (2010, background): “Alongside these neurobiological changes, increases in anxiety-like behaviours, hypervigilance and mild cognitive impairments have been reported (Meaney & Szyf, 2005; Sánchez et al., 2001).”
Maternal Care and Hippocampal Plasticity: Evidence for Experience-Dependent Structural Plasticity, Altered Synaptic Functioning, and Differential Responsiveness to Glucocorticoids and Stress (2008, background): “The maternal effects on behavioral and HPA responses to stress depend on, at least in part, epigenetic programming of gene expression (Meaney and Szyf, 2005; Diorio and Meaney, 2007).”
Epigenetics and the biological definition of gene x environment interactions. (2010, background): “…patterns are actively modified in mature (i.e., fully differentiated) cells, including, and perhaps especially, neurons and that such modifications can occur in animals in response to cellular signals driven by environmental events (Bird, 2007; Jirtle & Skinner, 2007; Meaney & Szyf, 2005).”
Etiologic Subtypes of Attention-Deficit/Hyperactivity Disorder: Brain Imaging, Molecular Genetic and Environmental Factors and the Dopamine Hypothesis (2007, background): “…or an indirect environmental effect of factors such as maternal diet (see Waterland & Jirtle, 2004; Dolinoy et al., 2006) or mother-child interactions (see Meaney & Szyf, 2005; Weaver et al., 2005) that can produce profound epigenetic changes as shown in proof-of-principle studies in animals.”
The Biological Implausibility of the Nature-Nurture Dichotomy & What It Means for the Study of Infancy (2011, background): “These proteins, in turn, are regulated by signals from outside the cell that can be as far removed as the behaviors of others (Champagne, 2008; Meaney & Szyf, 2005; Meaney, 2010).”
Epigenetic regulation in psychiatric disorders (2007, background): “Offspring of high-LG-ABN mothers are less anxious, have attenuated corticosterone responses to stress and display increased expression of glucocorticoid receptor ( GR ) mRNA and protein in the hippocampus when compared to pups of low-LG-ABN mother”
Social experience in early ontogeny has lasting effects on social skills in cooperatively breeding cichlids (2010, neutral): “…early social environment on social behaviour have been demonstrated in several vertebrates (e.g. fish, Moretz et al. 2007; birds, Adkins-Regan & Krakauer 2000; Bertin & Richard-Yris 2005; rodents, Bester-Meredith & Marler 2007; primates, Bastian et al. 2003; humans, reviewed in Meaney & Szyf 2005).”