Partitioning and plasticity of repressive histone methylation states in mammalian chromatin.

By A. Peters, S. Kubicek, K. Mechtler, Roderick J. O’Sullivan, A. Derijck, Laura Pérez-Burgos, Alexander Kohlmaier, Susanne Opravil, M. Tachibana, Y. Shinkai and 2 more. Molecules and Cells, 2003

1,214 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/190e78b2d771d084ee6c8a5d22377be587bf4956

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Citations in the corpus

• A double take on bivalent promoters. (2013, background): “H3K27me3 marks ;10%–15% of all H3 histones in ES cells as assessed by quantitative MS (Peters et al. 2003; Voigt et al. 2012).”
• Mechanisms of Polycomb gene silencing: knowns and unknowns (2009, background): “, whereas H3K27me and H3K27me2 seem to be more abundant and widesprea”
• Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity (2004, background): “The role of H3K27 methylation is not fully characterized, but it has been linked to transcriptional repression of euchromatic regions (Peters et al, 2003).”
• The diverse functions of histone lysine methylation (2005, background): “In mice, two Clr4 homologues, SUV39h1 and SUV39h2, are responsible for H3-K9 methylation at heterochromatic regions such as pericentric heterochromatin 18,48,49 .”
• Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery. (2012, neutral): “Free and monomethylated amino groups were chemically modified with propionic anhydride prior trypsin digestion (Peters et al., 2003).”
• DNA methylation and histone modifications: teaming up to silence genes. (2005, background): “G9a appears to be the enzyme predominantly responsible in mouse embryonic stem cells for the presence of H3K9me1 and H3K9me2 sites in euchromatic domains (see Glossary) [27].”
• High-resolution profiling of histone methylations in the human genome. (2007, background): “Previous evidence indicates that H3K27me1 is enriched in heterochromatin (Peters et al., 2003) or distributed broadly in euchromatic region but selectively depleted in active promoter regions (Vakoc et al., 2006).”
• Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. (2004, background): “The large size of the ubiquitin been previously described (Sewalt et al., 1998; Satijn et al., 1997;group compared to other histone modifications would Atsuta et al., 2001; Peters et al., 2003).”
• The profile of repeat‐associated histone lysine methylation states in the mouse epigenome (2005, methodology): “Generation and characterization of position- and state-specific methyl-lysine histone antibodies against H3-K9, H3-K27 and H4K20 has been described (Peters et al, 2003; Schotta et al, 2004).”