DNA methylation and histone modifications: teaming up to silence genes.

By François Fuks. Current Opinion in Genetics and Development, 2005

678 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/714770a3a468082c7e520e7890a2663f20f935de

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Citations in the corpus

Regulation of matrix metalloproteinase gene expression (2007, background): “Of these mechanisms, hypermethylation of a promoter has been well recognized as an efficientmeans of repressing transcription (Fuks, 2005).”
Pollutants inducing epigenetic changes and diseases (2019, background): “The methyl groups are acquired from S-adenosyl l-methionine and the target sites being the lysine and arginine residues of histones (Fuks 2005).”
Oxidative stress, DNA methylation and carcinogenesis. (2008, background): “) contribute to a transcriptional inactive chromatin state [2].”
Is folic acid good for everyone? (2008, background): “Methionine can be converted to the methyl-group donor S-adenosylmethionine (SAM), a molecule with many functions (113–115), including methylation of cytosine residues in DNA (116) and of arginine and lysine residues in histones (117, 118), both of which are involved in regulating gene expression (11”
MeInfoText: associated gene methylation and cancer information from text mining (2008, background): “…studies suggest that DNA methylation may be related to the interactions between DNA methyl-transferases, methyl-CpG binding proteins, histone deacetylases and histone methyltransferases and epigenetic information embodied in residue methylation states would flow from histone to DNA and back [35].”
The Role of Snail in EMT and Tumorigenesis (2013, background): “G9a interacts with DNA methyltransferases (DNMTs) directly and recruits it to target gene promoters for DNA methylation, whereas Suv39H1 creates an H3K9me3 binding and docking site for the adapter molecule HP1 which in turn recruits DNMT and HDAC to catalyze DNA methylation and histone deacetylation”
Chromosome territories. (2010, background): “Impressive progress has been achieved during the last decade with regard to the functional implications of DNA methylation, histone modifications, and chromatin remodeling events for gene regulation (Fuks 2005; Kouzarides 2007; Maier et al. 2008; Jiang and Pugh 2009).”