Linking DNA methylation and histone modification: patterns and paradigms

By H. Cedar, Y. Bergman. Nature reviews genetics, 2009

2,279 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/16f01a6aacb2722b5aca74c4cdf57d0bb6870f72

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

Citations in the corpus

The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers (2010, background): “Our study provides experimental evidence that at least 560 differentially methylated ubiquitously expressed genes are involved in generating molecular brain diversity in female honey bees. Although it is still unclear how methylation might be linked to the gene regulatory networks, it has been propo”
Dnmt3a is essential for hematopoietic stem cell differentiation (2011, background): “Histone modifications are thought to have a primary and dynamic role in the epigenetic regulation of gene expression during developmen”
DE NOVO EPIGENETIC PROGRAMS INHIBIT PD-1 BLOCKADE-MEDIATED T-CELL REJUVENATION (2017, positive): “transcription factors and epigenetic modifications are associated with changes in chromatin accessibility, recent evidence supports the notion that DNA methylation is a critical epigenetic mechanism for establishing stable gene-silencing programs (Bintu et al., 2016; Cedar and Bergman, 2009).”
Rethinking how DNA Methylation Patterns are Maintained (2009, background): “It is generally thought that patterns are established during embryonic development and are then faithfully inherited in somatic cells by a 'maintenance' mechanis”
Comprehensive Analysis of Silencing Mutants Reveals Complex Regulation of the Arabidopsis Methylome (2013, neutral): “Relationship between Histone Modifications and DNA Methylation There is growing evidence regarding interplays between histone modifications and DNAmethylation (Cedar and Bergman, 2009).”
Revealing the vectors of cellular identity with single-cell genomics (2016, methodology): “These methods hold promise for elucidating the epigenetic controls of cellular identity 193,194 .”
Epigenome-Wide Association Studies for common human diseases (2011, methodology): “This could be achieved using ChIP–seq experiments, either for the many histone modifications known to correlate with DNA”
Epigenetic choreographers of neurogenesis in the adult mammalian brain (2010, background): “DNA methylation at the 5-position of the nucleotide cytosine ring is relatively stable, and the maintenance DNA methyltransferase (Dnmt) ensures its epigenetic inheritance during DNA replicatio”
Prenatal environmental exposures, epigenetics, and disease (2011, positive): “Two examples include coordinated epigenetic modifications of chromatin by DNA methylation and posttranslational covalent modifications of histone proteins [4,11,12] and micro-RNA-induced suppression of gene expression during development [13].”
Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications (2016, background): “to access genes within the region [36].”