The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers

By F. Lyko, S. Forêt, R. Kucharski, S. Wolf, C. Falckenhayn, R. Maleszka. PLoS Biology, 2010

693 citations recorded by the source corpus.

Using genome-wide methylation profiles in honey bee queen and worker brains to understand how contrasting organismal outputs are generated from the same genotype.

Subfields: Ecology, Evolution, Behavior and Systematics, Genetics, Insect Science

View Paper: https://www.semanticscholar.org/paper/c2bd760cc0d5248fce171163c9d09bd72a3fa9f4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology, Evolution, Behavior and Systematics

1. Jay D. Evans
2. Alexandre V. Latchininsky
3. Jim M. Dunwell
4. R. Moritz
5. Hojun Song

In Genetics

1. Maria Alice Pinto
2. Jay D. Evans
3. Liam J. McGuffin
4. Alexandre V. Latchininsky
5. Jim M. Dunwell
6. R. Moritz
7. Hojun Song
8. G. Pfeifer

In Insect Science

1. Gregory A. Sword
2. Jay D. Evans
3. R. Moritz
4. L. Jaber
5. J. Enkerli

Citations in the corpus

• High-resolution genome-wide DNA methylation maps of mouse primary female dermal fibroblasts and keratinocytes (2014, neutral): “Recently, several single nucleotide resolution maps of DNA methylation in human [5,20], mouse [19], plants [4] and honey bee [21] have been possible because of long read-lengths of the high-throughput Illumina sequencing platform.”
• The mysterious presence of a 5-methylcytosine oxidase in the Drosophila genome (2013, background): “The Apis mellifera DNA methylation has been shown be to responsible for the generation of the different colony phenotypes in bees.(28)”
• Standard methods for molecular research in Apis mellifera (2013, background): “So far, four full methylomes (genome-wide methylation patterns) have been generated for Apis mellifera using the following tissues: adult brains of queens and workers and 96 hrs-old queen and worker larval heads (Lyko et al., 2010; Foret et al., 2012).”
• From Molecules to Management: Mechanisms and Consequences of Locust Phase Polyphenism (2017, background): “In their highly anticipated genome description (Wang et al., 2014), the authors also used DNA from a male locust captured in the southern island province of Hainan, which would be L. migratoria migratorioides according toMa et al. (2012).”