CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
By S. Nishimura, I. Manabe, M. Nagasaki, K. Eto, H. Yamashita, M. Ohsugi, M. Otsu, K. Hara, K. Ueki, S. Sugiura and 3 more. Nature Medicine, 2009
2,207 citations recorded by the source corpus.
Subfields: Epidemiology, Immunology
View Paper: https://www.semanticscholar.org/paper/0f3f252fb9de83d5a769bed8eedb897d6aab7cbe
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In Epidemiology
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In Immunology
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Citations in the corpus
- INFLAMMATION AND LIPID SIGNALING IN THE ETIOLOGY OF INSULIN RESISTANCE (2012, neutral): “…tissue and their activation state are influenced by other immune cell types that populate obese adipose tissue, including T cells, B cells, eosinophils, and mast cells (Feuerer et al., 2009; Kintscher et al., 2008; Liu et al., 2009; Nishimura et al., 2009; Winer et al., 2011; Wu et al., 2011).”
- The cellular and signaling networks linking the immune system and metabolism in disease (2012, background): “T cells in adipose tissue are believed to play a part in obesity-induced inflammation by modifying ATM numbers and their activation stat”
- Adipokines in inflammation and metabolic disease (2011, background): “CD8 + effector T cells and T H 1 cell-associated factors can initiate the recruitment and activation of macrophages in adipose tissues and promote a pro-inflammatory cascade that is associated with insulin resistanc”
- Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes. (2014, background): “[38] Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, et al.”
- Adipose Tissue in Obesity-Related Inflammation and Insulin Resistance: Cells, Cytokines, and Chemokines (2013, positive): “CD8 infiltration appears to be a key event preceding the depletion of adipose Tregs and the increased CD4 Th1 cell activation observed in murine models of diet-induced obesity [101, 102].”
- Fat Tissue, Aging, and Cellular Senescence (2010, background): “For example, antibody-mediated CD8+ deple- tion reduces high fat diet-induced TNFa, IL-6, and M1 macrophage abundance and improves insulin responsiveness in mice (Nishimura et al., 2009).”