Acetate Utilization and Butyryl Coenzyme A (CoA):Acetate-CoA Transferase in Butyrate-Producing Bacteria from the Human Large Intestine

By S. Duncan, A. Barcenilla, C. Stewart, S. Pryde, H. Flint. Applied and Environmental Microbiology, 2002

678 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Biotechnology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0e353aeb4f9c22cd9d93bc82bdfd444b8965c711

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. P. Louis
2. H. Flint
3. S. Duncan

In Molecular Biology

1. P. Louis
2. H. Flint
3. K. Scott
4. F. Bäckhed
5. S. Duncan
6. C. Meehan
7. P. Kovatcheva-Datchary
8. R. Ducatelle

Citations in the corpus

• Reduced Dietary Intake of Carbohydrates by Obese Subjects Results in Decreased Concentrations of Butyrate and Butyrate-Producing Bacteria in Feces (2006, neutral): “prausnitzii compared with Roseburia strains in pure culture (17).”
• Untangling the Genetic Basis of Fibrolytic Specialization by Lachnospiraceae and Ruminococcaceae in Diverse Gut Communities (2013, background): “have been associated with the production of butyrate necessary for the health of colonic epithelial tissue [10,11], and have been shown to be depleted in inflammatory bowel disease [12].”
• From the gut to the peripheral tissues: the multiple effects of butyrate (2010, positive): “The CoA transferase route is shown to be more dominant in the human butyrate-producing microbiota (26) .”
• Lactate-Utilizing Bacteria, Isolated from Human Feces, That Produce Butyrate as a Major Fermentation Product (2004, background): “Representatives of other abundant groups of butyrate-forming human colonic bacteria (17), R.”
• The Classification and Evolution of Bacterial Cross-Feeding (2019, methodology): “In general, the term “metabolic cross-feeding” is used according to this definition, though not further sub-divided according to characteristics of the relationship, as we shall here (Porcher et al., 2001; Doebeli, 2002; Duncan et al., 2002; Belenguer et al., 2006, 2008; MacLean et al., 2010; Egan e”
• The Controversial Role of Human Gut Lachnospiraceae (2020, background): “On the other hand, a net production of acetate has been assessed in some Coprococcus species through the acetate kinase pathway [46].”
• Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach (2005, background): “However, the precise microbial species or metabolites involved remain unknown. We share the current concept that the onset of CD could be due to an altered microbiota and that a dysbiosis could enhance the risk of disease. In that respect, the reduction in proportion of one microbial group is expect”
• Understanding the effects of diet on bacterial metabolism in the large intestine (2007, background): “2, 1b) has been described in several bacteria, for example, in the isolates from the rumen (Diez-Gonzalez et al. 1999) and human gut (Duncan et al. 2002).”
• A Phylogenomic View of Ecological Specialization in the Lachnospiraceae, a Family of Digestive Tract-Associated Bacteria (2014, background): “2013) and the abundance of butyric acid-producing species within the group (Bryant 1986; Duncan et al. 2002; Louis et al. 2004, 2010; Charrier et al. 2006).”