Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways.

By C. Serhan. Annual Review of Immunology, 2007

1,055 citations recorded by the source corpus.

Subfields: Biochemistry, Nutrition and Dietetics, Surgery

View Paper: https://www.semanticscholar.org/paper/08a71601f80fe1bf874375ea76e71ca0a1b033de

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. C. Serhan
2. T. Kern
3. Johnny Tang
4. N. Petasis
5. A. Mócsai
6. D. Gilroy
7. R. Medzhitov
8. Chia Nan

In Nutrition and Dietetics

1. C. Serhan
2. D. Gilroy
3. R. Medzhitov
4. N. Petasis
5. T. Kern
6. Johnny Tang
7. A. Mócsai
8. Chia Nan

In Surgery

1. R. Medzhitov
2. T. Kern
3. Johnny Tang
4. G. Hotamışlıgil
5. A. Mócsai
6. D. Gilroy
7. C. Serhan
8. N. Petasis

Citations in the corpus

• Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets (2008, background): “Furthermore, fatty acids, particularly linoleic and arachidonic acids, can be metabolized into a diverse and large family of bioactive lipid mediators called eicosanoids, which may function as pro- and anti-inflammatory mediator”
• Diverse novel functions of neutrophils in immunity, inflammation, and beyond (2013, background): “Apoptosis of neutrophils triggers an active process promoting resolution of inflammation (Serhan, 2007; Serhan et al., 2008; Soehnlein and Lindbom, 2010).”
• Resolvin D1 binds human phagocytes with evidence for proresolving receptors (2010, background): “LXA4 and RvD1 share some anti-inflammatory and proresolving actions in human and murine systems (9, 12, 30, 31), yet each is biosynthesized at different time intervals during resolution and via distinct biosynthetic routes (4).”
• Chronic Inflammation in Obesity and the Metabolic Syndrome (2010, background): “The activated endothelium allows extravasation of neutrophils and soluble components to the tissue, where they become activated releasing toxic agents and proteolytic enzymes to the extracellular milieu [27].”
• Origin and physiological roles of inflammation (2008, background): “Resolvins and protectins, which constitute another class of lipid mediator, as well as transforming growth factor-β and growth factors produced by macrophages, also have a crucial role in the resolution of inflammation, including the initiation of tissue repai”
• Pro-Resolving lipid mediators and Mechanisms in the resolution of acute inflammation (2014, background): “, 2009) and by downregulating extracellular release of superoxide in neutrophils along with macrophage inflammatory peptide 2 and IL-1b production (Serhan, 2007).”
• International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family (2009, background): “Besides its anti-inflammatory functions, LXA4 and its stable analog exhibit pro-resolution properties (Serhan, 2007).”
• Role of Antioxidants and Natural Products in Inflammation (2016, background): “Protectins and resolvins which constitute another class of lipid marker in addition to TGF-β and other growth factors generated from macrophages also have a vital role in the resolution of inflammation including the foundation of tissue repair [9, 10].”
• Inflammation in Diabetic Retinopathy (2011, positive): “Inflammation normally resolves promptly through a coordinated program that includes resolvins, lipoxins, and protectins (Serhan, 2007).”