Alternative splicing: new insights from global analyses.

By Benjamin J. Blencowe. Cell, 2006

1,155 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/049724305ed60528958073d0c64d39977bb82c72

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Citations in the corpus

RBPDB: a database of RNA-binding specificities (2010, background): “RNA-binding proteins (RBPs) have a fundamental role in a wide variety of cellular processes including transcription, RNA splicing and processing, localization, stability and translation (1–6).”
Spatiotemporal transcriptome of the human brain (2011, background): “Spatio-temporal differential exon usage Alternative exon usage is an important mechanism for generating transcript diversit”
RNA-binding proteins in human genetic disease. (2008, neutral): “proteins of the Argonaute-family to repress gene expression at the level of protein translation or affect mRNA stability by guiding cellular decay processes [ 95 ].”
Complexity of the Alternative Splicing Landscape in Plants[C][W][OPEN] (2013, background): “Research using various strategies has identified cis-acting sequence elements in exons and introns that are important for thecorrect recognition of pairs of splice sites (Blencowe, 2006; Chasin, 2007; Chen and Manley, 2009).”
Splicing regulation: from a parts list of regulatory elements to an integrated splicing code. (2008, background): “The major forms of AS are summarized in Figure 1A. Splicing regulation has been comprehensively described in several recent reviews (Black 2003; Konarska and Query 2005; Matlin et al. 2005; Blencowe 2006; House and Lynch 2008).”
The spliceosome: design principles of a dynamic RNP machine. (2009, background): “…spliced, that is, they are present in every mRNA produced from a given pre-mRNA, many are alternatively spliced (especially in higher eukaryotes) to generate variable forms of mRNA from a single pre-mRNA species (reviewed in Black, 2003; Blencowe, 2006; Graveley, 2001; Smith and Valcarcel, 2000).”
Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System (2008, background): “Alternative splicing of transcripts can enable a single gene to encode numerous protein products, greatly expanding its molecular complexity [9].”
Splicing in disease: disruption of the splicing code and the decoding machinery (2007, background): “Analyses of global splicing transitions in different biological systems has revealed coordinated regulation of subsets of alternative splicing events, representing a previously unappreciated layer of gene expression contro”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “Interestingly, graminaceous plants such as rice can take up Fe 2+ by OsIRT1 and OsIRT2 even without inducible 3+ resistance-associated macrophage protein) gene family encodes integral membrane proteins that transport a broad range of metal ions including Fe.”
The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation (2010, background): “…by trans-acting protein factors, which include the small nuclear ribonucleoproteins (snRNPs), the serine/arginine-rich (SR) family of nuclear phosphoproteins (SR proteins), SR-related proteins, and the heterogeneous nuclear ribonucleoproteins (hnRNPs) (Blencowe, 2006; Long and Caceres, 2009).”
StringTie enables improved reconstruction of a transcriptome from RNA-seq reads (2015, background): “The maximum flow in this network, where the flow follows the bias factor restrictions imposed by equation (1) above, represents the expression level associated with the predicted transcript.”
Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches (2009, background): “In addition, tremendous progress has been made using high-throughput methods, which has not only revealed many more new alternative splicing event”
The Logic of Chance: The Nature and Origin of Biological Evolution (2011, background): “The most prominent of such features in the genomes of multicellular eukaryotes include introns that ensure the possibility of alternative splicing, which occurs in the great majority of mammalian genes and constitutes the principal basis of proteome diversity (Blencowe, 2006; Wang, et al., 2008), an”