RNA-binding proteins in human genetic disease.

By Kiven Erique Lukong, Kai-Wei Chang, É. W. Khandjian, S. Richard. Trends in Genetics, 2008

820 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/518c8219f6b381f2cb34a763ca783893509ddae5

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Citations in the corpus

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (2012, neutral): “Against this background, it is unsurprising that numerous diseases have been linked to defects in RBP expression and function, including neuropathies, muscular atrophies, metabolic disorders, and cancer (Cooper et al., 2009; Darnell, 2010; Lukong et al., 2008).”
Revealing protein–lncRNA interaction (2015, background): “According to the pervasiveness of protein–RNA interactions, many reports underline how their perturbation is linked to pathologies, including autoimmune and metabolic diseases, neurological and muscular disorders and cancer [2, 13].”
Alternative RNA Conformations: Companion or Combatant (2022, background): “The triplex structure formed due to the interaction of MIR100HG and p27 promotes cell proliferation in triple-negative breast cancer through RNA–DNA interactions [92].”
RNA-Binding Proteins in Cancer: Old Players and New Actors. (2017, background): “Given their pivotal role in post-transcriptional events, it is not surprising that alterations to RBPs modus operandi underlie several pathological conditions [13].”
MicroRNA regulation by RNA-binding proteins and its implications for cancer (2011, background): “More than 500 human RBPs are known, but only a few have been assigned an oncogenic or tumour-suppressive function (reviewed in Ref”
Comprehensive Identification of RNA-Binding Domains in Human Cells (2016, background): “Due to their central role in cell biology, it is unsurprising that mutations in RBPs underlie numerous hereditary diseases (Castello et al., 2013a; Lukong et al., 2008).”