DNA methyltransferases control telomere length and telomere recombination in mammalian cells
By S. Gonzalo, I. Jaco, M. Fraga, Taiping Chen, E. Li, Manel Esteller, M. Blasco. Nature Cell Biology, 2006
625 citations recorded by the source corpus.
Subfields: Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/02281f1f8e9e22905abc06eb24e9350aa7d93b63
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Christoph Bock
- Linda Partridge
- Manuel Serrano
- Guido Kroemer
- Alexander Meissner
- H. Gu
- C. López‐Otín
- M. Blasco
In Physiology
- Manuel Serrano
- Guido Kroemer
- Linda Partridge
- M. Blasco
- C. López‐Otín
- Alexander Meissner
- Jesús Gil
- J. Campisi
Citations in the corpus
- The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers (2010, background): “Lastly, while methylation of sub-telomeric regions has been shown to be important for the control of telomere length and recombination [14], the honey bee telomeres are also not methylated (not shown).”
- Telomere length, stem cells and aging. (2007, background): “that are enriched in histone modifications characteristic of constitutive heterochromatin domain”
- Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. (2012, background): “Interestingly, the global CHOP that we observed in G34 mutants was particularly pronounced in subtelomeric regions, suggesting a possible mechanistic link with ALT in these tumors (Gonzalo et al., 2006).”
- The hallmarks of aging. (2013, background): “Mammalian telomeric repeats are also enriched for these chromatin modifications, indicating that chromosome ends are assembled into heterochromatin domains (Blasco, 2007b; Gonzalo et al., 2006).”
- The epigenetic regulation of mammalian telomeres (2007, background): “Recent studies have shown that mouse telomeric and subtelomeric chromatin contains histone modifications that are commonly found in heterochromati”
- Dnmt3a is essential for hematopoietic stem cell differentiation (2011, background): “Telomere integrity may also be affected, as Dnmt3a -null ES cells have elongated telomere”
- Transposable elements and the epigenetic regulation of the genome (2007, background): “However, recent studies show that the epigenetic status (predominantly DNA methylation) of telomeric and sub-telomeric repeats has a role in regulating telomere elongation in mammalian cell”