Transposable elements and the epigenetic regulation of the genome

By R. K. Slotkin, R. Martienssen. Nature reviews genetics, 2007

2,023 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/249ecf05963aa98067a367a140b3d784c2946858

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In Molecular Biology

1. Miho M. Suzuki
2. J. Brennecke
3. Elisabeth J. Chapman
4. Hiroyuki Sasaki
5. R. Jirtle
6. Cédric Feschotte
7. J. Goodier
8. Haig H. Kazazian

In Plant Science

1. J. Brennecke
2. Elisabeth J. Chapman
3. Cédric Feschotte
4. James C. Carrington
5. J. Goodier
6. Haig H. Kazazian
7. Ravi Sachidanandam
8. Carlos M. Duarte

Citations in the corpus

• DNA transposons and the evolution of eukaryotic genomes. (2007, background): “The proteins encoded by the pogolike Lemi1 element bind the TIRs and subterminal repeated motifs of the Arabidopsis Emigrant MITE: consequences for the transposition mechanism of MITEs.”
• Transcriptional Silencing of Transposons by Piwi and Maelstrom and Its Impact on Chromatin State and Gene Expression (2012, neutral): “…# 18198 (GD));; maelM391/maelDf (Findley et al, 2003) maelDf (DGRC: 150235) (rescue experiments) Short hairpin RNAi lines were cloned into the Valium-22 vector (Ni et al, 2011) modified with a white selection marker and integrated into the attp2 landing site reported in Markstein et al (2008).”
• Epigenetic silencing of transposable elements: a trade-off between reduced transposition and deleterious effects on neighboring gene expression. (2009, background): “In turn, silencing has effects on the expression of nearby genes (Iida et al. 2004; Lippman et al. 2004; Slotkin and Martienssen 2007; Zhang 2008).”
• DNA methylation landscapes: provocative insights from epigenomics (2008, background): “The idea that DNA methylation is primarily a mechanism of genome defence has received robust support from the analysis of fungal and plant genomes, in which transposable elements are evidently specific targets and are prevented from transposition by this modificatio”
• Transposable elements and the evolution of regulatory networks (2008, background): “In addition, there is evidence that some smRNAs are able to mediate homology-dependent transcriptional silencing and participate in the nucleation of heterochromati”
• An adaptive epigenetic memory in conifers with important implications for seed production (2012, background): “The need for silencing machinery may be an evolutionary response to TEs, and thus TEs appear to be the origin of all epigenetic phenomena, now present at both the level of single genes and across larger chromosomal regions (Slotkin and Martienssen, 2007).”
• Specialization and evolution of endogenous small RNA pathways (2007, background): “Endogenous siRNAs can arise from loci that contain direct or inverted repeats, and from dispersed repetitive element”
• Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. (2007, background): “functioning in the ‘repeat-associated small interfering RNA’ (rasiRNA) pathway, which acts in part to suppress transposable element activity (Slotkin and Martienssen, 2007).”
• Recent Insights into Mechanisms of Genome Size Change in Plants (2010, neutral): “[47] R.”
• Nothing in Genetics Makes Sense Except in Light of Genomic Conflict (2013, background): “This silencing inactivates newly established parasitic TEs that transpose during meiosis and spermatogenesis (Slotkin & Martienssen 2007).”
• Transposable elements contribute to activation of maize genes in response to abiotic stress (2014, neutral): “have now been documented (reviewed by [7]-[11]).”
• Climate Change Impacts on Seagrass Meadows and Macroalgal Forests: An Integrative Perspective on Acclimation and Adaptation Potential (2018, background): “Transposable elements, generally silenced by DNA methylation, can be activated by stress-induced de-methylation processes and move to new genomic locations (Zhang et al., 2006; Slotkin and Martienssen, 2007; Biémont, 2010; Seymour et al., 2014).”
• Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary (2009, background): “Transposable elements can be broadly categorized as retrotransposons (class I), which move via an RNA intermediate, or DNA transposons (class II), which mobilize through a ‘‘cut-andpaste’’ mechanism (Slotkin and Martienssen, 2007).”