The epigenetic regulation of mammalian telomeres
By M. Blasco. Nature reviews genetics, 2007
708 citations recorded by the source corpus.
Subfields: Aging, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/a7a2d9e8071cba58f55521a0df76a664eed29da2
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Aging
- Guido Kroemer
- Manuel Serrano
- Roderick J. O’Sullivan
- J. Karlseder
- R. Reddel
- Stefan Schoeftner
- Anthony J. Cesare
- Linda Partridge
In Molecular Biology
- Linda Partridge
- J. Karlseder
- Roderick J. O’Sullivan
- Manuel Serrano
- Stefan Schoeftner
- Anthony J. Cesare
- R. Reddel
- Guido Kroemer
In Physiology
- M. Blasco
- Manuel Serrano
- Guido Kroemer
- J. Karlseder
- Roderick J. O’Sullivan
- Linda Partridge
- Stefan Schoeftner
- C. López‐Otín
Citations in the corpus
- SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin (2008, neutral): “Mammalian telomeres are packaged in an unusual chromatin structure with features of heterochromatin 23,24 , but relatively little is understood about the role of chromatin modifications on telomere metabolism.”
- The hallmarks of aging. (2013, background): “Mammalian telomeric repeats are also enriched for these chromatin modifications, indicating that chromosome ends are assembled into heterochromatin domains (Blasco, 2007b; Gonzalo et al., 2006).”
- Transgenerational Epigenetic Inheritance: Prevalence, Mechanisms, and Implications for the Study of Heredity and Evolution (2009, neutral): “The dynamic nature of histones, their variability, and their association with every conceivable cellular function (see Berger 2007; Groth et al. 2007; Blasco 2007; Morris and Moazed 2007) makes understanding the inheritance of their specific structure and organization both challenging and urgent.”
- Telomeres: protecting chromosomes against genome instability (2010, background): “, and, therefore, telomeric chromatin is quite distinctiv”
- Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. (2008, neutral): “Telomeres are normally enriched in the heterochromatic marks H3K9me3 and H4K20me3 (Blasco 2007).”
- Alternative lengthening of telomeres: models, mechanisms and implications (2010, background): “It has also been suggested that the epigenetic state of the subtelomeric region can control telomeric recombinatio”
- Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II (2008, background): “Similar to pericentric heterochromatin, telomeric heterochromatin is thought to be fundamental for the maintenance of chromosomal integrit”