Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling

By D. Mukhopadhyay, Howard Riezman. Science, 2007

1,280 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/00b58f1ee2731465db5eb8fd8f1f7a66495e08bb

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Citations in the corpus

The cell biology of synaptic plasticity: AMPA receptor trafficking. (2007, background): “Ubiquitination can signal endocytosis to occur through specialized machinery that regulates clathrin endocytosis, and it has been implicated in the trafficking of receptor tyrosine kinases (Mukhopadhyay & Riezman 2007).”
Atypical ubiquitin chains: new molecular signals (2008, background): “…protein stability, cell-cycle progression, gene transcription, receptor transport, immune responses and viral infection (Haglund & Dikic, 2005; Mukhopadhyay & riezman, 2007). in general, these modifications are controlled by a three-step reaction initialized by E1-mediated activation of ub,…”
Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. (2007, background): “tion status of transcription factors and coregulators (96, 97).”
The ubiquitin–26S proteasome system at the nexus of plant biology (2009, background): “In addition, it is now known that there is also reversible ubiquitylation, which can direct non-proteolytic events that affect the regulation of transcription, chromatin structure and vesicular traffickin”
Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease. (2007, background): “regulation, and protein and membrane trafficking, without promoting substrate degradation [11].”
The ubiquitin code. (2012, background): “Nonproteolytic Functions of the Ubiquitin Code Ubiquitylation is also able to regulate signaling pathways, to attract trafﬁcking factors that change a substrate’s localization, or to control a substrate’s activity.”
Building ubiquitin chains: E2 enzymes at work (2009, background): “jpg" NDATA ITEM> ]> Ubiquitylation is a powerful mechanism for regulating most aspects of cell physiolog”
Origin and Function of Ubiquitin-like Protein Conjugation (2009, background): “The diversity of the processes regulated by ubiquitin–protein modification is extraordinar”
β-arrestin-mediated receptor trafficking and signal transduction (2011, background): “Ubiquitination of cell-surface receptors has emerged as an important post-translational modification that defines the trafficking itinerary of internalized receptors [73,74].”
Targeting the ubiquitin system in cancer therapy (2009, background): “With time, however, an increasing number of distinct functions have been assigned to different types of ubiquitin modification (for example, the addition of a single ubiquitin molecule or a ubiquitin chain), such as the regulation of protein trafficking, the assembly of protein signalling complexes,”
A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles (2011, background): “It is known that RTKs and other cell surface receptors can be ubiquitylated in their intracellular domains, and that the type of ubiquitylation then determines the fate of receptor molecules (6, 46).”