Mechanisms of axon ensheathment and myelin growth

By D. Sherman, P. Brophy. Nature Reviews Neuroscience, 2005

670 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/0026d956096c3523d31dab89d9e2f565fee4c19b

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In Cellular and Molecular Neuroscience

In Developmental Neuroscience

Citations in the corpus

Mammalian Rho GTPases: new insights into their functions from in vivo studies (2008, background): “A novel function for CDC42 has been suggested by studies of glial cells , which wrap multiple layers of their plasma membrane around axons to form myelin”
Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C (2010, background): “To obtain further evidence for the plasma membrane localization of Rab35, we analyzed the expression of Rab35 in myelin, a plasma membrane extension of oligodendrocytes which is formed during the development of the central nervous system by the spiral wrapping of glial membrane around the axons (She”
Directed differentiation of hippocampal stem/progenitor cells in the adult brain (2008, background): “2a–c ), suggesting that a fraction of AHP-derived oligodendrocytic cells might have the potential to myelinat”
Myelination and support of axonal integrity by glia (2010, background): “The ability of oligodendrocytes in the central nervous system (CNS) and Schwann cells in the peripheral nervous system (PNS) to wrap long segments of axons with a multilayered sheath of extended cell membrane ( Box 1 ), and to assemble a complex seal with the axon surface that defines the nodes of R”
Compartmentalizing the neuronal plasma membrane from axon initial segments to synapses. (2009, background): “NF186 and NF166 are expressed in neurons and localize to nodes and AIS, while NF155 is a glial isoform that is expressed in the paranodal loops contacting the axon adjacent to the nodes (Sherman and Brophy, 2005).”
Bace1 modulates myelination in the central and peripheral nervous system (2006, background): “Myelin is synthesized by oligodendrocytes in the central nervous system (CNS) or by Schwann cells in the peripheral nervous system (PNS”
Remyelination in the CNS: from biology to therapy (2008, background): “Second, a key function of the myelin sheath is that it organizes, at the node and paranode, the different voltage-dependent channels that are required for saltatory conductio”
Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication (2013, background): “Formation of functional axon-myelin units depends on bidirectional axon-glia interaction [1,2].”