I. I. C. Chio
Molecular Biology · 2014–2017
A researcher in the Science corpus: 3 papers; trusts 3 researchers and is trusted by 0 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 71 citations into it
Whom I. I. C. Chio trusts
Their strongest outbound trust, strongest first, inferred from their citations.
- Masayuki Yamamoto (in Molecular Biology)
- J. Hayes (in Molecular Biology)
- K. Itoh (in Molecular Biology)
Papers from I. I. C. Chio's perspective
Ordered by how strongly the researchers I. I. C. Chio trusts endorse each paper. Same corpus, a different order for every researcher.
- Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2 (Molecular and Cellular Biology)
- Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers (Proceedings of the National Academy of Sciences of the United States of America)
- Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation (Nature Genetics)
- BTB Protein Keap1 Targets Antioxidant Transcription Factor Nrf2 for Ubiquitination by the Cullin 3-Roc1 Ligase (Molecular and Cellular Biology)
- Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants (Proceedings of the National Academy of Sciences of the United States of America)
- Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy (Proceedings of the National Academy of Sciences of the United States of America)
- Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles (Genes to Cells)
- Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex (Molecular and Cellular Biology)
- Keap1 Recruits Neh2 through Binding to ETGE and DLG Motifs: Characterization of the Two-Site Molecular Recognition Model (Molecular and Cellular Biology)
- Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response. (Molecules and Cells)
Their papers
- Transcriptional Regulation by Nrf2 (2017) — 1,856 citations
- Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH (2015) — 849 citations
- Organoid Models of Human and Mouse Ductal Pancreatic Cancer (2014) — 1,928 citations