Zachary A. Knight

Molecular Biology · 2005–2010

A researcher in the Science corpus: 7 papers; trusts 3 researchers and is trusted by 3 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 85 citations into it; #9,156 of 17,773 by trust here, #4,105 by citations
• Pharmacology — 9 citations into it
• Computational Theory and Mathematics — 5 citations into it

Whom Zachary A. Knight trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. Christopher A. Lipinski
2. Yardena Samuels
3. J. Engelman
4. P. Cohen
5. D. Barbie
6. K. Inoki

Who trusts Zachary A. Knight overall

1. T. Yuan
2. David M. Sabatini
3. K. Imai
4. Lewis C. Cantley
5. Marcus Bantscheff
6. Jianming Zhang
7. D. Rubinsztein
8. M. Laplante

Papers from Zachary A. Knight's perspective

Ordered by how strongly the researchers Zachary A. Knight trusts endorse each paper. Same corpus, a different order for every researcher.

1. High Frequency of Mutations of the PIK3CA Gene in Human Cancers (Science)
2. Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification (Science)
3. The phosphatidylinositol 3-Kinase–AKT pathway in human cancer (Nature Reviews. Cancer)
4. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. (Cell)
5. Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. (Proceedings of the National Academy of Sciences of the United States of America)
6. The specificities of protein kinase inhibitors: an update. (Biochemical Journal)
7. The PIK3CA gene is mutated with high frequency in human breast cancers (Cancer Biology & Therapy)
8. Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex (Science)
9. Specificity and mechanism of action of some commonly used protein kinase inhibitors
10. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity (Nature)

Their papers

• A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. (2006) — 617 citations
• Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2 (2009) — 1,174 citations
• A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling (2006) — 1,146 citations
• Features of selective kinase inhibitors. (2005) — 647 citations
• Targeting the cancer kinome through polypharmacology (2010) — 673 citations
• T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR (2008) — 893 citations
• Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi* (2006) — 131 citations