Roberto Zoncu
Molecular Biology · 2002–2019
A researcher in the Science corpus: 10 papers; trusts 13 researchers and is trusted by 15 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 187 citations into it; #2,417 of 17,773 by trust here, #1,130 by citations
- Cell Biology — 52 citations into it; #277 of 2,073 by trust here, #120 by citations
- Immunology — 20 citations into it
- Aging — 17 citations into it; #251 of 261 by trust here, #101 by citations
- Endocrine and Autonomic Systems — 10 citations into it
Whom Roberto Zoncu trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
- Y. Sancak
- David M. Sabatini
- K. Inoki
- Dos D. Sarbassov
- M. Hansen
- C. Kenyon
- C. Thoreen
- Timothy R. Peterson
- L. Bar-Peled
- D. Guertin
Who trusts Roberto Zoncu overall
- David M. Sabatini
- Asier González González
- R. A. Saxton
- L. Bar-Peled
- T. Balla
- Michael N. Hall
- M. Laplante
- D. Hardie
- C. Settembre
- C. V. Dang
Papers from Roberto Zoncu's perspective
Ordered by how strongly the researchers Roberto Zoncu trusts endorse each paper. Same corpus, a different order for every researcher.
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex (Science)
- mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. (Cell)
- TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling (Nature Cell Biology)
- Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. (Molecules and Cells)
- Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. (Cell)
- TOR signaling in growth and metabolism. (Cell)
- Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. (Molecules and Cells)
- Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40 (Nature Cell Biology)
- Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. (Molecules and Cells)
- Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. (Developmental Cell)
Their papers
- mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the Vacuolar H+-ATPase (2011) — 1,614 citations
- mTOR: from growth signal integration to cancer, diabetes and ageing (2010) — 4,005 citations
- Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids (2010) — 2,430 citations
- The CoQ oxidoreductase FSP1 acts in parallel to GPX4 to inhibit ferroptosis (2019) — 3,124 citations
- The amino acid transporter SLC38A9 is a key component of a lysosomal membrane complex that signals arginine sufficiency to mTORC1 (2015) — 763 citations
- A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB (2012) — 1,872 citations
- An expanded Ragulator is a GEF for the Rag GTPases that signal amino acid levels to mTORC1 (2012) — 912 citations
- Origin of GABAergic neurons in the human neocortex (2002) — 709 citations
- Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling (2013) — 867 citations
- The lysosome as a cellular centre for signalling, metabolism and quality control (2019) — 759 citations