David E. Gloriam

Molecular Biology · 2006–2022

A researcher in the Science corpus: 19 papers; trusts 19 researchers and is trusted by 12 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 274 citations into it; #3,249 of 17,773 by trust here, #2,765 by citations
• Cellular and Molecular Neuroscience — 114 citations into it; #626 of 2,998 by trust here, #269 by citations
• Computational Theory and Mathematics — 51 citations into it
• Computational Biology & Bioinformatics — 34 citations into it
• Nutrition and Dietetics — 22 citations into it
• Sensory Systems — 8 citations into it
• Structural Biology — 8 citations into it
• Biomedical Engineering — 7 citations into it

Whom David E. Gloriam trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. W. James Kent
2. Robert Fredriksson
3. Aron Marchler-Bauer
4. Peter M. Rice
5. Heiko A. Schmidt
6. Vignir Ísberg
7. Peter Mombaerts
8. Thóra K. Bjarnadóttir
9. Stephen H. Bryant
10. Christian Munk

Who trusts David E. Gloriam overall

1. Gáspár Pándy-Szekeres
2. Albert J. Kooistra
3. Christian Munk
4. Stefan Mordalski
5. Lim Heo

Papers from David E. Gloriam's perspective

Ordered by how strongly the researchers David E. Gloriam trusts endorse each paper. Same corpus, a different order for every researcher.

1. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.
2. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.
3. Genes and ligands for odorant, vomeronasal and taste receptors (Nature Reviews Neuroscience)
4. BLAT--the BLAST-like alignment tool. (Genome Research)
5. How many drug targets are there?
6. The ChEMBL bioactivity database: an update
7. SIFTS: Structure Integration with Function, Taxonomy and Sequences resource
8. Structure-Function of the G-protein-Coupled Receptor Superfamily (Annual Review of Pharmacology and Toxicology)
9. Drug discovery: a historical perspective. (Science)
10. Crystal structure of opsin in its G-protein-interacting conformation (Nature)

Their papers

• GPCRDB: an information system for G protein-coupled receptors (2013) — 507 citations
• 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology (2018) — 228 citations
• Trends in GPCR drug discovery: new agents, targets and indications (2017) — 2,288 citations
• Generic GPCR Residue Numbers - Aligning Topology Maps Minding The Gaps (2014) — 453 citations
• Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse. (2006) — 435 citations
• GPCRdb in 2021: integrating GPCR sequence, structure and function (2020) — 298 citations
• Selectivity determinants of GPCR-G protein binding (2017) — 336 citations
• GPCRdb in 2018: adding GPCR structure models and ligands (2017) — 500 citations
• The G protein-coupled receptor subset of the rat genome (2007) — 201 citations
• Integrating structural and mutagenesis data to elucidate GPCR ligand binding (2016) — 56 citations
• An Online Resource for GPCR Structure Determination and Analysis (2019) — 118 citations
• GPCRdb: an information system for G protein-coupled receptors (2015) — 377 citations
• Combinatorial expression of functionally distinct GPCR isoforms can diversify receptor signalling response (2020) — 118 citations
• Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors (2019) — 216 citations
• GPCRdb: the G protein‐coupled receptor database – an introduction (2016) — 195 citations
• A Structural Framework for GPCR Chemogenomics: What's In a Residue Number? (2018) — 5 citations
• Structure of the class D GPCR Ste2 dimer coupled to two G proteins (2020) — 70 citations
• GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources (2022) — 165 citations
• Pharmacogenomics of GPCR Drug Targets (2018) — 545 citations