Cahir O'Kane

Epidemiology · 1996–2011

A researcher in the Science corpus: 7 papers; trusts 3 researchers and is trusted by 0 researchers here, as inferred from the citation graph.

Subfields

• Epidemiology — 44 citations into it
• Cellular and Molecular Neuroscience — 33 citations into it
• Neurology — 19 citations into it
• Cell Biology — 15 citations into it

Whom Cahir O'Kane trusts

Their strongest outbound trust, strongest first, inferred from their citations.

1. N. Mizushima (in Epidemiology)
2. D. Rubinsztein (in Epidemiology)
3. D. Klionsky (in Epidemiology)

Papers from Cahir O'Kane's perspective

Ordered by how strongly the researchers Cahir O'Kane trusts endorse each paper. Same corpus, a different order for every researcher.

1. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing (EMBO Journal)
2. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. (Science)
3. Escape of Intracellular Shigella from Autophagy (Science)
4. Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein* (Journal of Biological Chemistry)
5. The tor pathway: a target for cancer therapy (Nature Reviews. Cancer)
6. Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study. (Journal of Clinical Oncology)
7. Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis (Nature Cell Biology)
8. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. (Molecules and Cells)
9. CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
10. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease (Proceedings of the National Academy of Sciences of the United States of America)

Their papers

• Rapamycin alleviates toxicity of different aggregate-prone proteins. (2006) — 682 citations
• Lysosomal positioning coordinates cellular nutrient responses (2011) — 856 citations
• Novel targets for Huntington’s disease in an mTOR-independent autophagy pathway (2008) — 816 citations
• Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. (2007) — 617 citations
• Stereotypic and random patterns of connectivity in the larval mushroom body calyx of Drosophila. (2005) — 89 citations
• Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease (2004) — 2,455 citations
• Associative Learning Disrupted by Impaired Gs Signaling in Drosophila Mushroom Bodies (1996)