Escape of Intracellular Shigella from Autophagy

By Michinaga Ogawa, T. Yoshimori, Toshihiko Suzuki, H. Sagara, N. Mizushima, C. Sasakawa. Science, 2005

865 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/60e927375ff7e83665015720dedcb9a1f5c1880c

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Citations in the corpus

Toll‐like receptors control autophagy (2008, methodology): “HeLa cells were maintained in DMEM, 10% FBS. BMMs were derived from C57/BL6 mice or GFP–LC3 mice (Dr N Mizushima, Japan) as described previously (Via et al, 1998).”
Recent Advances in Understanding Enteric Pathogenic Escherichia coli (2013, background): “Moreover, the T3S effectors VirA and IcsB help Shigella to circumvent its autophagymediated degradation (492, 493).”
Autophagy in inflammation, infection, and immunometabolism (2021, background): “This was soon followed by studies recognizing autophagy’s impact on Shigella (Ogawa et al., 2005), Salmonella (Birmingham et al.”
Septins: the fourth component of the cytoskeleton (2012, background): “flexneri has to be able to polymerize actin and recruit septi”
History of lectins: from hemagglutinins to biological recognition molecules. (2004, result): “However, in contrast to the direct tagging of Shingella flexneri by autophagy related gene 5 (ATG5) [73], it was observed that galectin-8 does not bind to the bacterial glycans but to the host cell’s own complex glycans that become accessible in the damaged vesicles.”
Autophagy: process and function. (2007, background): “2004) and Shigella flexneri (icsB mutant) (Ogawa et al. 2005), are sequestered by large autophagosomes or autophagosome-like structures and degraded following fusion with lysosomes.”
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. (2009, background): “…and Parkinson’s and Huntington’s diseases, and also is involved in degradation of invasive microbes (Liang et al., 1999; Qu et al., 2003; Yue et al., 2003; Gutierrez et al., 2004; Ravikumar et al., 2004; Ogawa et al., 2005; Sugimoto, 2007; Levine and Kroemer, 2008; Mizushima et al., 2008).”
Molecular mechanisms of Escherichia coli pathogenicity (2012, background): “Interestingly, the secreted effector IcsB can bind VirG and sequester it, thereby avoiding another aspect of host defenc”
Another way to die: autophagic programmed cell death (2005, neutral): “It has more recently been shown that autophagy is also involved in the killing of bacteria that are ingested by cells.(5,6) The molecular basis of autophagy has been extensively studied, mainly in yeasts, by investigation of autophagy-”