Transcriptional regulation of metabolism.

By B. Desvergne, L. Michalik, W. Wahli. Physiological Reviews, 2006

932 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/fe13b2a1eb6c443f2c1f3b04539954895e817cfa

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. D. Tocher

In Molecular Biology

1. Johan Auwerx
2. L. Hue
3. C. Cantó
4. D. Tocher
5. B. Torstensen
6. J. Loor
7. A. Jetten
8. H. Taegtmeyer

In Physiology

1. Johan Auwerx
2. D. Tocher
3. C. Cantó
4. B. Torstensen
5. Sander M. Houten
6. B. Björnsson
7. A. Jetten
8. G. Turchini

Citations in the corpus

• Nutritional management of the transition cow in the 21st century – a paradigm shift in thinking (2013, background): “Unlike classical endocrine receptors that bind to high-affinity glandular hormones, PPAR bind to lower-affinity ligands generated from dietary fat or intracellular metabolism and turn on feed-forward metabolic cascades to regulate lipid homeostasis via the transcription of genes involved in lipid me”
• Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation. (2008, background): “Cell M organs to nutrient availability (Desvergne et al., 2006; Feige and Auwerx, 2007; Spiegelman and Heinrich, 2004).”
• Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism (2009, background): “The expression of estrogen-related receptor α (ERRα) and peroxisome proliferators-activated receptors (PPARs) α, β, and γ, which are implicated in the control of lipid homeostasis as well, was not changed in RORαsg/sg mice [Desvergne et al., 2006; Tremblay and Giguere, 2007].”
• The Randle cycle revisited: a new head for an old hat. (2009, background): “PPARs do not act on one single target but rather orchestrate several pathways whereby nutrients regulate their own metabolism (40).”
• Towards Fish Lipid Nutrigenomics: Current State and Prospects for Fin-Fish Aquaculture (2008, background): “, LXR and FXR), and those activated by fatty acids and their metabolites, such as PPARs (Desvergne et al., 2006).”
• Gene networks driving bovine milk fat synthesis during the lactation cycle (2008, background): “Genes involved in FA transport such as LPL, CD36, and ACSL1 are peroxisome proliferator-activated receptor gamma (PPARγ) target genes [91].”