Intercellular adhesion, signalling and the cytoskeleton

By C. Jamora, Elaine Fuchs. Nature Cell Biology, 2002

606 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/3ff6be12ca241c8a5c349ef737ad2a0a9cfbee3f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

In Molecular Biology

Citations in the corpus

Intermediate filaments: from cell architecture to nanomechanics (2007, background): “In addition, disturbances in signalling pathways, as caused by mutations in IF proteins, could be responsible for some aspects of IF-related diseases in genera”
Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis (2007, background): “The homophilic interaction complexes between E-cadherin molecules of two apposed cell membranes are stabilized by the adaptor proteins β-catenin and α-catenin , and actin filament”
Adhesion-dependent cell mechanosensitivity. (2003, background): “A review of this topic in any detail is way beyond our scope here but can be found in several recent review articles (Jamora & Fuchs 2002, for cell-cell junctions; Geiger et al. 2001, Zamir & Geiger 2001, for cell-matrix adhesions).”
Deconstructing the cadherin-catenin-actin complex. (2005, positive): “Binding between cadherin extracellular domains is relatively weak, but cell-cell adhesion may be strengthened by lateral clustering of cadherins mediated by protein linkages between the cadherin cytoplasmic domain and the actin cytoskeleton (Jamora and Fuchs, 2002).”
Formation and function of the myofibroblast during tissue repair. (2007, background): “Furthermore, adhesion-dependent survival signals are transmitted via cell–cell contacts and cadherins (Jamora and Fuchs, 2002; Yap and Kovacs, 2003) and formation of homotypic cadherin junctions is a possible signal of the presence of myofibroblast accumulation in late granulation tissue.”
α-Catenin Is a Molecular Switch that Binds E-Cadherin-β-Catenin and Regulates Actin-Filament Assembly (2005, positive): “The intracellular domain of cadherins binds cytoplasmic proteins that are thought to recruit and organize actin filaments (Gumbiner, 2000; Jamora and Fuchs, 2002).”
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. (2004, background): “…and N-cadherin, as well as that of c-Myc and integrin signaling, raises the intriguing possibility of a complex network linking adhesion to specific signaling cascades in stem cells attached to their niche (Jamora and Fuchs 2002; Schwartz and Ginsberg 2002; Perez et al. 2003; Arai et al. 2004).”
A renaissance for SRC (2004, background): “In addition to their role as cell–matrix attachment structures, providing the structural and mechanical properties that are necessary for adhesion, they also participate in cell-signalling processes that regulate proliferation and gene transcriptio”