Natural killer cells, viruses and cancer

By A. Cerwenka, L. Lanier. Nature reviews. Immunology, 2001

949 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/f5b4d5ba5a88ecbf3edb730fe8af42ce3623c37f

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Citations in the corpus

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression (2003, background): “Natural killer cells are lymphocyte effector cells of the innate immune system that may be important in protecting against tumour developmen”
Dendritic cells as therapeutic vaccines against cancer (2005, background): “) or NK cells (which recognize MHC-class-I-deficient tumour cell”
Increase of regulatory T cells in the peripheral blood of cancer patients. (2003, background): “NK cells are an effective part of the innate antitumor response (13).”
Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF-β11 (2009, background): “N atural killer cells play important roles in innate immunity, and are also involved in the activation of adaptive immunity by cross-talking with dendritic cells (DCs)(4) and promoting a Th1-mediated immunity (1).”
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis (2004, background): “FcRγ or DAP12 associates with several specific immunoreceptors for cell activation in myeloid lineage cell”
Induced recruitment of NK cells to lymph nodes provides IFN-γ for TH1 priming (2004, background): “Activated NK cells kill target cells and produce inflammatory cytokines such as tumor necrosis factor and IFN-γ, thereby acting as primary mediators of innate immunity in peripheral inflamed tissue”
Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function (2003, background): “These cell types include NK T and NK cells in the blood, liver, spleen, and bone marrow (1, 2).”
Immunology of COVID-19: Current State of the Science (2020, positive): “They are therefore able to induce the lysis of virus-infected cells that upregulate virus-derived proteins, as well as stress-inducible ligands, which are then recognized by NK cellactivating receptors, such as NKp46 (Cerwenka and Lanier, 2001; Draghi et al., 2007; Duev-Cohen et al., 2016; Glasner e”
New aspects of natural-killer-cell surveillance and therapy of cancer (2002, background): “gif" NDATA ITEM> ]> Natural-killer (NK) cells are white blood lymphocytes of the INNATE IMMUNE SYSTEM that have diverse biological functions, including recognition and destruction of certain microbial infections and neoplasm”