Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow.

By Y. Katayama, M. Battista, W. Kao, A. Hidalgo, A. Peired, S. Thomas, P. Frenette. Cell, 2006

1,405 citations recorded by the source corpus.

Subfields: Developmental Neuroscience, Hematology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f484d813b03954fa904c628160f3da644a6bb6d5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Developmental Neuroscience

1. S. Morrison

In Hematology

1. S. Morrison
2. P. Frenette
3. D. Scadden

In Molecular Biology

1. A. Engler
2. Dennis E. Discher
3. S. Morrison
4. D. Scadden
5. P. Frenette
6. Gregory E. Miller
7. E. Chen
8. P. Yurchenco

Citations in the corpus

• Rhythmic modulation of the hematopoietic niche through neutrophil clearance (2013, neutral): “Physiological regulation of these stromal components modulates HSPC survival and trafficking, and is afforded by several mechanisms including sympathetic innervation (Katayama et al., 2006; Mendez-Ferrer et al., 2008), signals derived from macrophages (Chow et al.”
• Matrix elasticity directs stem cell lineage specification. (2006, background): “Adam J. Engler,1,2 Shamik Sen,1,2 H. Lee Sweeney,1 and Dennis E. Discher1,2,3,4,* 1Pennsylvania Muscle Institute 2School of Engineering and Applied Science 3Cell & Molecular Biology Graduate Group 4Physics Graduate Group University of Pennsylvania, Philadelphia, PA 19104, USA *Contact:…”
• Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche (2011, methodology): “The SNS is required for progenitor egress (Katayama et al., 2006; Méndez-Ferrer et al., 2010a), suggesting that G-CSF– mediated increase of sympathetic tone in the BM may represent a putative M-independent target.”
• Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells (2006, background): “Notably, G-CSF treatment reduces SDF-1 transcription and the number of endosteal osteoblast”
• Uncertainty in the niches that maintain haematopoietic stem cells (2008, background): “Mice deficient in UDP-galactose ceramide galactosyltransferase, an enzyme that is required for normal peripheral nerve myelination and conduction, fail to mobilize haematopoietic progenitors in response to granulocyte colony-stimulating factor (G-CSF”