Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition.

By Katrina L. Bogan, Charles Brenner. Annual review of nutrition, 2008

708 citations recorded by the source corpus.

Subfields: Geriatrics and Gerontology, Oncology, Physiology

View Paper: https://www.semanticscholar.org/paper/e89075ea099bb103d4b5357ec4d53f539455dc19

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Geriatrics and Gerontology

1. Johan Auwerx
2. C. Cantó
3. Keir J. Menzies
4. R. Houtkooper
5. R. Wanders
6. S. Imai
7. E. Verdin
8. Jun Yoshino

In Oncology

1. Johan Auwerx
2. C. Cantó
3. R. Houtkooper
4. S. Imai

In Physiology

1. Johan Auwerx
2. C. Cantó
3. Keir J. Menzies
4. R. Houtkooper
5. R. Wanders
6. E. Verdin
7. S. Imai
8. D. Sinclair

Citations in the corpus

• The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet induced obesity (2012, neutral): “Unfortunately, NA treatment often leads to severe flushing, resulting in poor patient compliance (Bogan and Brenner, 2008).”
• NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus (2015, background): “NA and NAM, collectively termed niacin or vitamin B3, are now known as precursors for NAD+, an essential element for all cells (Bogan and Brenner, 2008; Chi and Sauve, 2013; Houtkooper et al., 2010a).”
• The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways. (2010, background): “The NRK1 isoform is ubiquitously expressed, whereas NRK2 localization seems to be restricted to heart, brain, and muscle (44).”
• Therapeutic potential of NAD-boosting molecules: the in vivo evidence (2018, neutral): “…the product of CD38 and the PARPs (Magni et al., 1999, 2004) or from the various forms of niacin taken up in the diet, including NAM, NA, nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN) (Bogan and Brenner, 2008; Mills et al., 2016; Trammell et al., 2016b; Ummarino et al., 2017).”
• NAD+ Biosynthesis and Signaling in Plants (2018, result): “The levels of NADþ and NADP in these compartments were found to vary under light conditions in a range from 0.1mM to 2mM, which is similar to intracellular concentrations in yeast (Bogan and Brenner, 2008) and also was similar to what was found in isolated chloroplasts (Takahama et al., 1981).”