The role of Atg proteins in autophagosome formation.

By N. Mizushima, T. Yoshimori, Y. Ohsumi. Annual Review of Cell and Developmental Biology, 2011

2,863 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology, Parasitology

View Paper: https://www.semanticscholar.org/paper/e6c51c7654ddedd4660d8554d9ec681c545f3cc0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. N. Mizushima
2. D. Klionsky
3. Beth Levine
4. E. White
5. T. Johansen
6. I. Slaninová
7. M. Komatsu
8. T. Yoshimori

In Molecular Biology

1. N. Mizushima
2. D. Klionsky
3. Paul D. Thomas
4. Huaiyu Mi
5. E. White
6. T. Yoshimori
7. M. Komatsu
8. Pascale Gaudet

In Parasitology

1. N. Mizushima
2. Katherine R Parzych
3. D. Klionsky
4. E. White
5. T. Johansen
6. T. Lamark
7. M. Komatsu
8. Chang S. Chan

Citations in the corpus

• Exploring autophagy with Gene Ontology (2016, background): “5,25,26 Many studies have also been performed in human as well as model organisms such as mouse, and to a lesser extent in Drosophila melanogaster, Caenorhabditis elegans or Arabidopsis thaliana .”
• Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. (2014, background): “, the rest of the cytoplasm is largely absent from the autophagosome (Mizushima et al., 2011).”
• The LIR motif – crucial for selective autophagy (2013, background): “Amphisomes also fuse with lysosomes to form autolysosomes (Mizushima et al., 2011) (Fig.”
• The BioGRID interaction database: 2017 update (2016, background): “This process is mediated by a core set of 18 autophagy (ATG) proteins that drive membrane formation to mediate both selective and non-selective degradation (41).”
• The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. (2012, neutral): “autophagosome (Mizushima et al., 2011; Tooze and Yoshimori, 2010).”
• Autophagy: Renovation of Cells and Tissues (2011, background): “Recent studies suggest that additional membranes derived from the Golgi complex, the mitochondria, and the plasma membrane also contribute to autophagosome formation (Hailey et al., 2010; Mizushima et al., 2011; Ravikumar et al., 2010; Tooze and Yoshimori, 2010).”
• TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation (2012, neutral): “Its functions encompass programmed cell survival and cell death, normally skewed toward cell survival through provision of energy and nutrients and ridding the cytoplasm of toxic macromolecular aggregates, faulty organelles (Mizushima et al., 2011), and invading microorganisms (Deretic, 2012b; Levin”
• An Overview of Autophagy: Morphology, Mechanism, and Regulation (2014, background): “The source of membrane that makes up the phagophore is highly debated, but various studies have implicated the plasma membrane (120, 121), ER (41, 155), Golgi complex (134), and mitochondria (36) as possible sources (107, 145).”