Autophagy: Renovation of Cells and Tissues

By N. Mizushima, M. Komatsu. Cell, 2011

6,040 citations recorded by the source corpus.

Subfields: Epidemiology, Pharmacology, Physiology

View Paper: https://www.semanticscholar.org/paper/c463fd6c71920efff206a5ed48c91091ddc0b3e5

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Citations in the corpus

To be or not to be? How selective autophagy and cell death govern cell fate. (2014, neutral): “Engaging Autophagy The process of macroautophagy (herein, autophagy) is best understood in the context of nutrient starvation (Kroemer et al., 2010; Mizushima and Komatsu, 2011).”
Septins: the fourth component of the cytoskeleton (2012, background): “Diseases that are characterized by defective autophagy include cancer, neurodegenerative diseases, ageing, autoimmune diseases and inflammatory disease”
Autophagy in Human Diseases. (2020, background): “Macroautophagy (Panel A) is mediated by the autophagosome.(1-5) A por-”
The LIR motif – crucial for selective autophagy (2013, background): “…autophagy is highly relevant for a number of diseases, including cancer, neurodegenerative diseases, muscular dystrophy, lipidstorage disorders and processes such as development, ageing and innate immunity (Levine and Kroemer, 2008; Levine et al., 2011; Mizushima and Komatsu, 2011; Deretic, 2012).”
ER stress-induced cell death mechanisms. (2013, background): “Pioneering studies in yeast delineated many of the essential components of the autophagic machinery, subsequently confirmed and extended in mammalian systems [49].”
Cellular senescence and its effector programs (2014, background): “…activation of anabolic and catabolic processes during senescence (Narita et al. 2011). mTOR is a nutrient-sensitive kinase that promotes global protein translation and ribosome biogenesis and inhibits the ULK1 complex, which initiates autophagosome formation (Mizushima and Komatsu 2011).”
Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy (2015, neutral): “For instance, one of the most important adaptive responses that is induced to maintain cellular survival under stress conditions is autophagy 21 .”
Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms (2019, background): “Moreover, blocking autophagy has been associated with neurodegenerative diseases such as Parkinson's and Alzheimer's disease (182) (183) (184) .”
Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy (2018, background): “During the early neonatal starvation period, autophagy is needed to provide adequate amino acids and energy (Kuma et al., 2004; Mizushima and Komatsu, 2011).”