Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma.

By Caroline Leventhal, Shahin Rafii, Dahlia Rafii, A. Shahar, S. Goldman. 1999

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Citations in the corpus

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “The initial suggestive evidence came from observations of increased neuronal differentiation of adult rat SVZ explants in coculture with endothelial cells (Leventhal et al., 1999).”
A Neurovascular Niche for Neurogenesis after Stroke (2006, background): “Imitola J, Raddassi K, Park KI, Mueller FJ, Nieto M, Teng YD, Frenkel D, Li J, Sidman RL, Walsh CA, Snyder EY, Khoury SJ (2004) Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway.”
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. (2000, background): “A likely endogenous source of BDNF for newly generated neurons in the adult rat subependymal zone are vascular endothelial cells that contain and secrete BDNF but not other neurotrophins (Leventhal et al. 1999).”
The brain tumor microenvironment (2011, background): “The identities of these factors is slowly beginning to emerge and some of these reportedly include, BDNF (Leventhal et al., 1999), PEDF (Ramirez-Castillejo et al.”
Presenilin 1 mutants impair the self-renewal and differentiation of adult murine SVZ-neuronal progenitors via cell autonomous mechanisms involving Notch signaling (2010, background): “, 2006), endothelial cells (Leventhal et al., 1999; Shen et al., 2004) or astrocytes (Song et al.”
Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk‐1 protein expression (2005, background): “BDNF is required for basal neurogenesis (Lee et al., 2002) and can bemodulated by astrocytes and endothelial cells to support neuronal differentiation (Kirschenbaum &Goldman, 1995; Leventhal et al., 1999; Song et al., 2002).”
Making a tumour's bed: glioblastoma stem cells and the vascular niche (2007, background): “The precise cocktail of vascular-derived factors that regulate neural stem cells remains to be determined, but brain-derived neurotrophic factor ( BDNF ), vascular endothelial growth factor C ( VEGFC ) and pigment epithelium-derived factor are likely candidate”
Brain-derived Neurotrophic Factor Is Stored in Human Platelets and Released by Agonist Stimulation (2002, background): “Recently we and others have demonstrated that vascular human endothelial cells produce and secrete BDNF (19, 42, 44).”
Brain micro-ecologies: neural stem cell niches in the adult mammalian brain (2008, background): “123 follicle and nervous system has revealed common and unique features (figure 1; reviewed in Spradling et al. 2001; Doetsch 2003b; Fuchs et al. 2004; Li & Xie 2005).”
Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. (2004, background): “Factors involved might be FGF2 (11), PDGF (29), brain-derived neurotrophic factor (30), and IL-8 (31), which have the capacity to induce mitogenesis, differentiation, recruitment, and survival of NPCs and newly generated neurons.”
A Specialized Vascular Niche for Adult Neural Stem Cells (2008, background): “Endothelial cells are a source of diffusible signals, such as VEGF, FGF2, IGF1, PEDF, BDNF, and unidentified factors that affect neural precursors (Biro et al., 1994; Jin et al., 2002; Leventhal et al., 1999; Ramirez-Castillejo et al., 2006; Shen et al., 2004).”