Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk‐1 protein expression

By Vivi M. Heine, Jessica Zareno, S. Maslam, Marian Joëls, P. Lucassen. 2005

222 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. H. Schmidt
2. J. Warner-Schmidt
3. Christopher Pittenger
4. R. Duman
5. T. Madsen
6. E. Nestler
7. Bruce S. McEwen
8. Fred H. Gage

In Developmental Neuroscience

1. R. Duman
2. H. Schmidt
3. J. Warner-Schmidt
4. Christopher Pittenger
5. T. Madsen
6. Bruce S. McEwen
7. Fred H. Gage
8. E. Nestler

In Molecular Biology

1. R. Duman
2. T. Madsen
3. H. Schmidt
4. J. Warner-Schmidt
5. Christopher Pittenger
6. E. Nestler
7. V. Krishnan

Citations in the corpus

• Human Hippocampal Neurogenesis Persists throughout Aging (2018, neutral): “…volume were blunted in older humans (60–77 years) compared with younger people (Maass et al., 2015), suggesting vascular niche signaling pathways (Heine et al., 2005; Thored et al., 2007; Warner-Schmidt and Duman, 2007) and blood-born factors (Katsimpardi et al., 2014) sustaining angiogenesis…”
• Electroconvulsive seizure restores neurogenesis and hippocampus‐dependent fear memory after disruption by irradiation (2008, background): “VEGF immunoreactivity is expressed at high levels in astrocytes and endothelial cells, and at lower levels in neurons in the hippocampus (Heine et al., 2005).”
• Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms (2008, background): “VEGF, a trophic factor induced by electroconvulsive seizure (Newton et al, 2003), is suppressed by chronic stress (Heine et al, 2005).”
• The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “Proliferation of newborn cells in the SGZ of the hippocampus is decreased in animal models of depression that incorporate stress components, including chronic unpredictable stress (Alonso et al., 2004; Heine et al., 2005), acute and chronic restraint stress (Pham et al.”
• Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment (2006, background): “In addition, a recent study has demonstrated that stress decreases levels of vascular endothelial growth factor (VEGF) in the hippocampus (Heine et al., 2005).”