Building the mammalian heart from two sources of myocardial cells

By Margaret E. Buckingham, S. Meilhac, S. Zaffran. Nature reviews genetics, 2005

1,250 citations recorded by the source corpus.

Subfields: Epidemiology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/df7de8edb1ad757a1ac07cc0952105226f4e2f60

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In Epidemiology

In Genetics

Deepak Srivastava

In Molecular Biology

Citations in the corpus

The developmental genetics of congenital heart disease (2008, background): “Discovery of a 'second' heart field (SHF) led to a rethinking of the origin and patterning of the embryonic hear”
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. (2006, positive): “Can Be Clonally Expanded on Feeder Layers of Cardiac Mesenchyme Several markers of early cardiogenic progenitors, includingNkx2.5,GATA4, andGATA6, continue to be expressed in differentiated cardiomyocytes and thus do not allow one to distinguish between progenitors of the crescent stage and differen”
Production of De Novo Cardiomyocytes: Human Pluripotent Stem Cell Differentiation and Direct Reprogramming (2012, neutral): “The cardiac mesoderm gives rise to the endocardium, the first heart field (FHF, which forms the atria, left ventricle, and the nodal conduction system), the secondary heart field (SHF, which forms the right ventricle, outflow tract, and part of the atria), and the proepicardial mesenchyme (Buckingha”
Retinoic acid in development: towards an integrated view (2008, background): “The SHF is a population of undifferentiated cardiac precursor cells originating from the pharyngeal mesoderm and lying medial to the cardiac crescent (also termed first heart field) (see Ref”
Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. (2010, background): “For extensive coverage, readers are directed to a number of excellent recent reviews on this issue (56, 108, 308, 379, 380).”
Making or breaking the heart: from lineage determination to morphogenesis. (2006, methodology): “More recent studies using Cre-lox lineage analysis and retrospective clonal lineage analysis indicate that the heart tube derived from the FHF may predominantly provide a scaffold upon which cells from a second heart field (SHF) migrate and build the requisite cardiac chambers (Buckingham et al., 20”
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. (2007, background): “The heart is one of the most conserved organs at the molecular level (Buckingham et al., 2005; Olson, 2006; Srivastava, 2006) and is the organ most affected by disease in childhood and adult populations (Thom et al., 2006).”