Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.

By B. Rose, T. Force, Yibin Wang. Physiological Reviews, 2010

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Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets (2015, background): “Results of these studies have previously been extensively reviewed (Bernardo et al. 2010; Martin et al. 2014; Rose et al. 2010).”
Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update. (2012, background): “p38 activity has been implicated in the differentiation of p19 cells into cardiomyocyte-like cells; however, this mechanism, as with the studies of BMP signaling, has not been well characterized (53, 235, 299).”
Glucagon-like peptide 1 (GLP-1) (2019, background): “Treatment of isolated mouse cardiomyocytes with either exendin4 or GLP-1 (936amide) increases phosphorylation of AKT and ERK [631], both of which are known to positively affect cardiomyocyte growth and survival [632,633].”
TNFα Shedding in Mechanically Stressed Cardiomyocytes is Mediated by Src Activation of TACE (2015, background): “, 2002] that is responsible for a number of cardiac pathologies [Rose et al., 2010], although the underlying mechanism of Src activation of p38 is unknown.”