Making or breaking the heart: from lineage determination to morphogenesis.
By Deepak Srivastava. Cell, 2006
679 citations recorded by the source corpus.
Subfields: Epidemiology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/ab9ee5acee29afc13f18c96a0344d3663bc60871
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Epidemiology
In Molecular Biology
- B. Bruneau
- K. Nishikura
- Alecia N. Muth
- Deepak Srivastava
- Kathryn N. Ivey
- Yibin Wang
- B. Rose
- T. Force
Citations in the corpus
- Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair (2007, background): “Improvement of myocardial function can be achieved with circulating or resident stem cells, which requires their isolation, in vitro propagation, and transplantatio”
- Functional consequences of developmentally regulated alternative splicing (2011, background): “5) in mice, after which growth occurs primarily via hypertrophic pathways (cell growth) rather than hyperplastic pathways (cell proliferation”
- MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. (2008, positive): “In addition to the numerous transcription factors and signaling molecules that control development of cardiac cells (Srivastava, 2006), miRNAs have a critical role in cardiac differentiation in vivo (Zhao et al.”
- Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. (2007, background): “The heart is one of the most conserved organs at the molecular level (Buckingham et al., 2005; Olson, 2006; Srivastava, 2006) and is the organ most affected by disease in childhood and adult populations (Thom et al., 2006).”
- Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors (2010, background): “Embryonic stem cells possess clear cardiogenic potential, but efficiency of cardiac differentiation, risk of tumor formation, and issues of cellular rejection must be overcome (Ivey and Srivastava, 2006; Laflamme et al., 2007; Nussbaum et al., 2007; van Laake et al., 2008).”
- Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage (2012, neutral): “Many of these genes have important roles in heart development and their dysregulation is associated with heart defects and cardiovascular disease (Bruneau, 2008; Srivastava, 2006).”
- The developmental genetics of congenital heart disease (2008, background): “The regulatory mechanisms involved in establishing the early heart and regulating its morphogenesis have been studied extensivel”
- Functions and Regulation of RNA Editing by ADAR Deaminases (2010, background): “Interestingly, miR-1 plays a critical role in the development of embryonic heart (62).”
- Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. (2010, background): “For extensive coverage, readers are directed to a number of excellent recent reviews on this issue (56, 108, 308, 379, 380).”