Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification.

By A. Moretti, L. Caron, Atsushi Nakano, J. Lam, Alexandra Bernshausen, Yinhong Chen, Y. Qyang, Lei Bu, Mika Sasaki, S. Martin-Puig and 4 more. Cell, 2006

1,090 citations recorded by the source corpus.

Subfields: Electrical and Electronic Engineering, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/63e4409239bc22bf9e314cf208e1fcc3a0e84369

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Charles E. Murry
2. G. Keller
3. B. Bruneau
4. Nikolaos G. Frangogiannis

In Surgery

1. G. Keller
2. Charles E. Murry
3. Nikolaos G. Frangogiannis

Citations in the corpus

• The developmental genetics of congenital heart disease (2008, background): “Intriguingly, the cardiovascular lineages — myocardial, endocardial and smooth muscle — all derive from common precursors that sequentially branch off as specialized cell type”
• Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. (2008, methodology): “5, whereas the transcription factor Isl1 selectively marks the secondary heart field, giving rise to much of the right ventricle and outflow tracts (Ema et al., 2006; Moretti et al., 2006; Wu et al., 2006).”
• Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. (2011, background): “Using cues from developmental biology, significant advances have been made in our understanding of cardiac differentiation from mouse and human ESCs and findings from these studies have demonstrated that one of the earliest stages of differentiation, the induction of cardiac mesoderm, can be monitor”