Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction

By G. Davidson, Wei Wu, Jinlong Shen, J. Bilić, U. Fenger, P. Stannek, A. Glinka, Christof Niehrs. Nature, 2005

559 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/df4cda7cb5bdc78f88c3ae61cf1df415f9ec8057

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In Genetics

1. Christof Niehrs
2. S. Angers
3. K. Willert
4. K. Jones
5. Z. Steinhart

In Molecular Biology

1. Christof Niehrs
2. S. Angers
3. K. Willert
4. K. Jones
5. Z. Steinhart
6. Hans Clevers
7. R. Nusse

Citations in the corpus

• Wnt signaling: is the party in the nucleus? (2006, background): “Other central Wnt regulators that are known to translocate in and out of the nucleus include Dsh (for review, see Habas and Dawid 2005), -catenin (Giannini et al. 2000), ICAT (Tago et al. 2000), and the regulatory kinases CK1, CK2, and GSK3 .”
• Wnt/beta-catenin signaling in development and disease. (2006, unknown): “Recent studies have indicated that the coreceptor LRP5/6 interacts with Axin through five phosphorylated PPP(S/T)P repeats in the cytoplasmic tail of LRP (Davidson et al., 2005; Zeng et al., 2005).”
• CDK8 is a colorectal cancer oncogene that regulates β-catenin activity (2008, unknown): “Samples were obtained from the following five sites: the Massachusetts General Hospital (25), the Brigham and Women’s Hospital/Dana Farber Cancer Institute (46), the Vall d’Hebron Hospital in Barcelona (9) and the Genomics Collaborative Incorporated (43).”
• Function and biological roles of the Dickkopf family of Wnt modulators (2006, background): “Upon Wnt-Fz interaction, Lrp6 becomes phosphorylated by Casein kinase 1g, which allows Axin to bind to Lrp6 (Davidson et al., 2005; Zeng et al., 2005).”
• Wnt signaling in development and tissue homeostasis (2018, background): “…and the Cdk14(PFTK1)-Cyclin Y mitotic kinase complex (Davidson et al., 2009) then phosphorylate PPPSP motifs within the intracellular region of LRP5/6, thereby priming them for further phosphorylation by the membrane-anchored kinase casein kinase 1 γ (Davidson et al., 2005; Zeng et al., 2005).”
• Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. (2010, unknown): “2B) (Davidson et al. 2005; Bilic et al. 2007; Schwarz-Romond et al. 2007).”