Function and biological roles of the Dickkopf family of Wnt modulators

By Christof Niehrs. Oncogene, 2006

1,015 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/3df694cb70a7d219054b5688fe824660266ed5e1

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In Molecular Biology

1. Radu M. Suciu
2. Armand B. Cognetta Jr.
3. B. Cravatt
4. Zachary E. Potter
5. Cristina Cruciat
6. Christof Niehrs

Citations in the corpus

• Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling (2018, positive): “1 − 3 Wnt signaling is regulated by diverse mechanisms, including inhibitory binding proteins (Dickkopf proteins 4 ) and post-translational modi fi cations (PTMs).”
• Secreted and transmembrane wnt inhibitors and activators. (2013, background): “Whereas the amino-terminal CRD, DKK_N, is unique to the Dkks, the carboxy-terminal CRD shows homology with the colipase fold, a domain found in a wide range of functionally unrelated proteins, including, for example, colipases, toxins, protease inhibitors, and prokineticins (Niehrs 2006).”