Exosomes: endosomal-derived vesicles shipping extracellular messages.

By Benoît Février, G. Raposo. Current Opinion in Cell Biology, 2004

1,075 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ded6143cab2b724533c98800eb69dfdd79d51f81

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Citations in the corpus

Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery. (2013, background): “Exosomes are formed in the multivesicular body (MVB) by the invagination of the endosomal membrane and are released to the extracellular space when MVB fuses with plasma membrane [20].”
Exosomal cell-to-cell transmission of alpha synuclein oligomers (2012, background): “Indeed, exosomes are biologically active vesicles that are thought to be important for intercellular communication [93,94].”
Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes (2012, background): “They are produced by many cell types and are involved in intercellular signalling (3,4).”
The regulation of exosome secretion: a novel function of the p53 protein. (2006, background): “It has been suggested that exosomes may play a role in several different physiologic processes (17).”
Intravesicular Localization and Exocytosis of α-Synuclein and its Aggregates (2005, background): “Interestingly, there is an increasing body of evidence that the export of classical cytosolic proteins is a common phenomenon, because other leader-less proteins, such as galectins, thioredoxin, heat shock proteins, and certain cytoskeletal proteins, are also secreted from cells through unconvention”
Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes. (2008, neutral): “Am J Respir Cell Mol Biol 2004;31(1):114–21.”
Interaction and uptake of exosomes by ovarian cancer cells (2011, methodology): “CD9 is a tetraspanin protein that has been used as exosome marker [32,33].”
Astrocytes and Glioblastoma cells release exosomes carrying mtDNA (2009, methodology): “In order to investigate if mtDNA is associated to the exosomal fraction, exosomes were further purified by magnetic beads coated with a CD9 antibody.”
Exosomes: a common pathway for a specialized function. (2006, background): “(2) Unknown mechanism may lead MVBs toward the plasma membrane where proteins such as SNAREs and synaptogamins would allow their fusion and the consequent release of the ILVs in the extracellular medium as exosomes.”
Exosomes in Tumor Microenvironment Influence Cancer Progression and Metastasis (2013, background): “In a second step, these multivesicular endosomes (also referred to as multivesicular bodies (MVB)) fuse with the cellular membrane to release exosomes into the extracellular space [3, 7].”