Exosomes: a common pathway for a specialized function.

By Guillaume van Niel, Isabel Porto-Carreiro, Sabrina Simoes, G. Raposo. Journal of Biochemistry (Tokyo), 2006

923 citations recorded by the source corpus.

Subfields: Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5f7bf5ebe0366eb726acba754208ce771fc87e62

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In Infectious Diseases

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Citations in the corpus

Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages1 (2007, background): “These latter findings suggest an alternative model of IL-1 release that may involve the P2X7Rinduced formation of MVB that contain exosomes with entrapped IL-1 (Fig.”
Circulating microRNAs as stable blood-based markers for cancer detection (2008, background): “Exosomes are 50- to 90-nm (24), membrane-bound particles that have been reported to be abundant in plasma (25) and that have recently been shown (in cell culture studies) to contain miRNAs (26).”
Biological functions of microRNAs: a review (2011, background): “Exosomes are small (50–90 nm) membrane vesicles of endocytic origin that are released into the extracellular environment upon fusion of multivesicular bodies (MVB) with the plasma membrane [ 64 ].”
Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival (2010, background): “-Synuclein is exported in association with membrane vesicles that have the hallmarks of exosomes We addressed the question of whether the nonclassical -synuclein secretion occurred via externalized membrane vesicles (Cooper and Barondes, 1990; Denzer et al., 2000; van Niel et al., 2006).”
Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes. (2008, neutral): “Blood Cells Mol Dis 2005;34(3): 214–9.”
Characterization of human plasma-derived exosomal RNAs by deep sequencing (2013, background): “Background Many cells produce exosomes [1-3], small (30–100 nm) membrane vesicles that are released into the extracellular environment by fusing with the plasma membrane [4].”
Exosomes--vesicular carriers for intercellular communication. (2009, background): “Exosome biogenesis Exosomes correspond to the intraluminal vesicles (ILVs) of endosomal MVBs that fuse with the cell surface in an exocytic manner [3 ,4,5].”
The tetraspanin CD63 regulates ESCRT-independent and dependent endosomal sorting during melanogenesis (2011, background): “…many physiological processes including cessation of growth factor signaling, lysosomal degradation, exosome secretion, lysosome related organelle (LRO) biogenesis, and perhaps even amyloid formation (Raiborg and Stenmark, 2009; Raposo et al., 2007; Simons and Raposo, 2009; van Niel et al., 2006).”
Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials. (2012, background): “All exosomes, whether secreted by cells in culture into their media, or by various organs into associated bodily fluids, have been suggested to participate in intercellular communication, either supporting or perturbing (in the case of cancer) different physiological processes [4,39,40].”
Exosome Function: From Tumor Immunology to Pathogen Biology (2008, background): “However, recently, the endocytic network has also been demonstrated to contain an alternative secretory pathway (6).”
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis (2011, background): “…vesicles are generated by direct shedding from the plasma membrane (Bianco et al., 2009; Cocucci et al., 2009), others are formed within the endosomal system by the budding of the limiting endosomal membrane into its lumen inducing the formation of multivesicular endosomes (van Niel et al., 2006).”