In Brief

By H. Lee, Jennifer M. Lund, B. Ramanathan, N. Mizushima, A. Iwasaki. Nature reviews. Immunology, 2007

822 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/ddcaca8d3b3ff870766aaf9d5920da9f47cadc79

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Citations in the corpus

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors (2010, background): “The pDCs that lack autophagy-related protein Atg5, which fail to induce autophagosome formation, show defects in the production of interferon-α after infection with vesicular stomatitis viru”
Pattern recognition receptors and inflammation. (2010, background): “pDCs take advantage of a cellular process called autophagy in which self-proteins and damaged organelles are degraded in double-membraned vesicles called autophagosomes (Lee et al., 2007).”
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis (2007, background): “As it is now known that toll-like receptor 7 (TLR7)-mediated detection of viral replication is autophagy dependan”
Autophagy: process and function. (2007, background): “However, it was recently demonstrated that cytosolic replication intermediates are also recognized by TLR7 following transportation to endosomes/lysosomes via autophagy, leading to interferon-␣ secretion by plasmacytoid dendritic cells (Lee et al. 2007).”
Toll‐like receptors control autophagy (2008, methodology): “Autophagy has a role in innate and adaptive immunity (Levine and Deretic, 2007; Schmid and Munz, 2007) as a mechanism for elimination of intracellular bacteria, including M. tuberculosis, Listeria monocytogenes, Streptococcus pyogenes, Salmonella and Shigella (Rich et al, 2003; Gutierrez et al,…”
PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity (2012, background): “This requires both TLR and Atg5 signaling in DCs (134–137).”
Autophagy, Immunity, and Microbial Adaptations (2009, background): “Autophagy is proinflammatory, e.g., when autophagy captures cytosolic viral replication intermediates and delivers them to the lumen of endosomal compartments where they meet their cognate PRRs, as in the case with viral single-stranded RNA and Toll-like receptor (TLR) 7 (Lee et al., 2007).”
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012, neutral): “phology and immunofluorescence patterns, thereby providing statistically meaningful data.(311) This method can also be used for endogenous LC3, and, therefore, is useful for nontransfected primary cells.”